Results 11 to 20 of about 1,812,118 (303)
Influence of imipramine on the duration of immobility in chronic forced-swim-stressed rats. [PDF]
, 2004 We studied the influence of imipramine on the duration of immobility in chronic forced-swim-stressed rats. Both single and chronic administration of imipramine potently shortened immobility in naive rats during forced-swim testing.
Araki, Hiroaki +5 more
core +1 more source
Bioethics and animal testing. A review of scientific praxis in Mexico
Revista Colombiana de Bioética, 2018 This study examines the experimental use of non-human animals in Mexico from a bioethical approach. For this purpose, a survey was applied to researchers who develop research lines with animals (specifically chordates) to know the ethical and technical ...
Luis Alberto Contreras Armas +3 more
doaj +1 more source
Animals, 2023 In 2016, the Dutch government declared its commitment to phasing out animal experiments by 2025. Although a high number of animal experiments are still performed and the 2025 target will not be met, the commitment remains.
Lara Andreoli +4 more
doaj +1 more source
EURL ECVAM Status Report on the Development, Validation and Regulatory Acceptance of Alternative Methods and Approaches (2016) [PDF]
, 2016 Replacement, Reduction and Refinement of animal testing is anchored in EU legislation. Alternative non-animal approaches facilitate a shift away from animal testing.
ASTURIOL BOFILL DAVID +30 more
core +1 more source
Neuroimaging as a selection tool and endpoint in preclinical and clinical trials [PDF]
, 2016 Standard imaging in acute stroke enables the exclusion of non-stroke structural CNS lesions and cerebral haemorrhage from clinical and pre-clinical ischaemic stroke trials. In this review, the potential benefit of imaging (e.g., angiography and penumbral
Macrae, I. Mhairi, Muir, Keith W.
core +2 more sources
Frontiers in Toxicology, 2023 Introduction: The positive identification of xenobiotics and their metabolites in human biosamples is an integral aspect of exposomics research, yet challenges in compound annotation and identification continue to limit the feasibility of comprehensive ...
Breanne Kincaid +6 more
doaj +1 more source
Testing natural biomaterials in animal models [PDF]
, 2016 Animal models have been extensively developed in the last decades in biomedical field. Their use has shown particular relevance in fields such as cell biology, genetics, anatomy and development, biochemistry, infection and immunity, cancer research ...
Costa‐Pinto, Ana +3 more
core +1 more source
Current Animal Models of Postoperative Spine Infection and Potential Future Advances. [PDF]
, 2015 Implant related infection following spine surgery is a devastating complication for patients and can potentially lead to significant neurological compromise, disability, morbidity, and even mortality.
Bernthal, NM +7 more
core +1 more source
Derecho Animal, 2018 The increasing awareness of animal sentience is bringing relevant changes to society and a growing commitment to guaranteeing their wellbeing. Portugal has been making its way in a solid, even if slow, manner, including through the approval of legal ...
Helena Correia Mendonça
doaj +1 more source
Effects of different simplified milk recording methods on genetic evaluation with test-day animal model [PDF]
, 2007 The aims of the present study were to compare estimated breeding values (EBV) for milk yield using different testing schemes with a test-day animal model and to evaluate the effect of different testing schemes on the ranking of top sheep.
Cacioppo, D. +4 more
core +3 more sources