FDA-approved drugs that are spermatotoxic in animals and the utility of animal testing for human risk prediction. [PDF]
J Assist Reprod Genet, 2018 Rayburn ER +5 more
europepmc +1 more source
BEHAVIOUR OF MILK RING TEST ON MILKS OF SOME FARM ANIMALS WITH SPECIAL REFERENCE TO A MODIFIED SERUM RING TEST [PDF]
, 2000 openalex +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Farewell to Animal Testing: Innovations on Human Intestinal Microphysiological Systems. [PDF]
Micromachines (Basel), 2016 Kang TH, Kim HJ.
europepmc +1 more source
Evaluation of centrally tested swine with an animal model
, 1989 R. N. Goodwin
openalex +2 more sources
Concerns over future market projections . . . . Urges involvement in animal-assisted programs . . . . Responses to definition of truth . . . . Favors early spay/neuter . . . . Suggests ways to enhance practitioners’ research capabilities . . . . Feels in-house laboratory testing is not enough [PDF]
, 2000 openalex +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley +1 more source
Tests for systemic animal insecticides, using dogs and triatominae [PDF]
, 1981 Mário B. Aragão +2 more
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