Results 321 to 330 of about 262,015 (339)

Risk assessment: alternatives to animal testing

1997
All new chemicals manufactured specifically for use in food are required to be evaluated for safety. Such chemicals which are intentionally incorporated into foods are additives, and this chapter focuses on their safety assessment. Each proposed food additive is subjected to various in vivo and in vitro assays, which may include tests for genotoxicity,
R. D. Combes, C. L. Broadhead, M. Balls
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Advancing alternative methods to reduce animal testing

Science
Emerging approaches show promise for regulatory ...
Chad P, Nelson, Paul, Brown, Suzanne, Fitzpatrick, Kevin A, Ford, Paul C, Howard, Tracy, MacGill, Edward E C, Margerrison, Jacqueline, O'Shaughnessy, Tucker A, Patterson, Rakesh, Raghuwanshi, Rodney, Rouse, Selen, Stromgren, Kyung E, Sung, Luis G, Valerio, Jeffrey L, Ward, Namandjé N, Bumpus   +15 more
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The new paradigm in animal testing – “3Rs alternatives”

Regulatory Toxicology and Pharmacology
Regulatory studies have revolutionised over time. Today, the focus has shifted from animal toxicity testing to non-animal for regulatory safety testing. This move is in line with the international 3Rs (Replacement, Reduction, and Refinement) principle and has also changed the regulator's perspective.
Wen Tsin, Poh, Johnson, Stanslas
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Charting a course for cell culture alternatives to animal testing*1

Fundamental and Applied Toxicology, 1986
Cell culture systems (CCS) are finding increasing use in toxicology. They supplement and amplify existing tests in animals, and play a special role in the iterative process involved in studies of mechanisms of toxic action. The need is stressed for adequate standardization and validation of CCS, and meticulous conduct of tests using such systems.
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The use of alternatives to animal tests in developing countries.

Developments in biological standardization, 1999
Consideration of alternative methods for animal tests in developing countries is important because good quality laboratory animals and proper animal facilities are not always sufficiently available to perform the currently required quality control tests.
Hong, HA, Hendriks, J
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Lords support animal testing but call for alternatives

BMJ, 2002
Animal experiments are necessary, but more needs to be done to develop and promote alternative methods, says the House of Lords Select Committee on Animals in Scientific Procedures. In a new report the committee recommends the setting up of research units to find ways of reducing the need for animals and replacing them.
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Alternatives to Animals in Toxicity Testing

Scientific American, 1989
John M. Frazier, Alan M. Goldberg
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Genetic testing in prostate cancer management: Considerations informing primary care

Ca-A Cancer Journal for Clinicians, 2022
Veda N Giri, Jacob E Berchuck, Mary-ellen Taplin   +2 more
exaly  

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Paulo Cáceres Guido, Jun J Mao, Lorenzo Cohen   +2 more
exaly  

Advances In Animal Alternatives For Safety And Efficacy Testing

1997
Presents up-to-date concepts and approaches to the theory and practice of alternatives to animal testing and promotes technology transfer. The text addresses some of the ramifications of the National Institutes of Health Revitalization Act of 1993 which instructs the NIH to fund replacement, reduction and refinement alternatives.
openaire   +2 more sources