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Alternatives to animal testing: A review [PDF]
Saudi Pharmaceutical Journal, 2015 The number of animals used in research has increased with the advancement of research and development in medical technology. Every year, millions of experimental animals are used all over the world. The pain, distress and death experienced by the animals during scientific experiments have been a debating issue for a long time. Besides the major concern
Doke SK, Dhawale SC.
exaly +5 more sources
Alternatives to animal testing to assess MASH drugs and hepatotoxicity. [PDF]
Hepatology, 2023 The Food and Drug Administration (FDA) Modernization Act 2.0 “allows for alternatives to animal testing for purposes of drug and biological product applications.” This provides an opportunity to develop and improve alternatives to animal studies to assess drugs in the liver.
Brenner DA, Brenner DA.
europepmc +4 more sources
Alternatives to Animal Testing [PDF]
Journal of Toxicology: Cutaneous and Ocular Toxicology, 1994 Animal experimentation has long been a controversial issue with impassioned arguments on both sides of the debate. Increasingly it has become more expedient and feasible to develop new methods that avoid the use of animals. There is agreement on both sides that reduction and refinement of experiments on animals should be an important goal for the ...
H. Kojima, T. Seidle, H. Spielmann
semanticscholar +9 more sources
Curated Data In - Trustworthy In Silico Models Out: The Impact of Data Quality on the Reliability of Artificial Intelligence Models as Alternatives to Animal Testing. [PDF]
Altern Lab Anim, 2021 New Approach Methodologies (NAMs) that employ artificial intelligence (AI) for predicting adverse effects of chemicals have generated optimistic expectations as alternatives to animal testing.
Alves VM +7 more
europepmc +2 more sources
Novel computational models offer alternatives to animal testing for assessing eye irritation and corrosion potential of chemicals. [PDF]
Artif Intell Life Sci, 2021 Eye irritation and corrosion are fundamental considerations in developing chemicals to be used in or near the eye, from cleaning products to ophthalmic solutions.
Silva AC +8 more
europepmc +2 more sources
Cosmetics, 2022 Almost a decade after the stipulated deadline in the 7th amendment to the EU Cosmetics Directive, which bans the marketing of animal-tested cosmetics in the EU from 2013, animal experimentation for cosmetic-related purposes remains a topic of animated ...
Slobodanka Tamburic
exaly +2 more sources
Alternatives to animal testing: current status and future perspectives. [PDF]
Arch Toxicol, 2011 On the occasion of the 20th anniversary of the Center for Alternative Methods to Animal Experiments (ZEBET), an international symposium was held at the German Federal Institute for Risk Assessment (BfR) in Berlin.
Liebsch M +8 more
europepmc +2 more sources
In silico methods – Computational alternatives to animal testing
ALTEX, 2018 A seminar and interactive workshop on “In silico Methods – Computational Alternatives to Animal Testing” was held in Berlin, Germany, organized by Annemarie Lang, Frank Butt- gereit and Andrea Volkamer at the Charite-Universitatsmedizin Berlin, on August 17-18, 2017. During the half-day seminar, the variety and applications of in silico methods as
Lang, Annemarie +8 more
openaire +4 more sources
Harmonisation of Animal Testing Alternatives in China
Alternatives to Laboratory Animals, 2017 More and more countries are lining up to follow the EU's approach and implement a full ban on the sale of cosmetics that have been tested on animals, which has been the case in the EU since 2013. Besides animal welfare considerations, the need for mutual acceptance of data (MAD) and harmonisation of the global market have made the move toward non ...
Shujun, Cheng, Xiaoting, Qu, Yao, Qin
openaire +3 more sources
Antibody-based alternatives to animal testing for toxin detection and antitoxin evaluation [PDF]
Frontiers in ToxicologyAnimal experiments have long played a central role in biomedical research and toxicology, yet their limitations in translational accuracy and ethical concerns have intensified the demand for reliable alternatives.
Seo-Hyuk Chang +17 more
doaj +2 more sources