Results 211 to 220 of about 1,948,245 (257)

Ammonia Accumulation Drives Intervertebral Disc Degeneration by Triggering Ammonia‐Induced Cell Death Through Lysosome–Mitochondria Crosstalk

open access: yesCell Proliferation, EarlyView.
Mechanical strain disrupts the lysosome‐mitochondria axis via GLS1‐mediated ammonia toxicity, causing NP cell death and ECM breakdown in IVDD. CB839‐mediated GLS1 inhibition effectively rescues cellular homeostasis and alleviates disc degeneration.
Yang Zhang   +11 more
wiley   +1 more source

The Datafication of Community Health Work: Discipline, Visibility and the State

open access: yesDevelopment and Change, EarlyView.
ABSTRACT There has been a concerted drive to expand the scope of ‘data for development’, with a focus on novel technologies. This article highlights a relatively overlooked category of worker in the large‐scale production of such data: volunteers. The authors examine community health as the last frontier of the ‘datafication’ of health, but which forms
Kathy Dodworth, Jean‐Benoît Falisse
wiley   +1 more source

The Role of Research Funders in Promoting Ethical International Health Research Collaborations

open access: yesDeveloping World Bioethics, EarlyView.
ABSTRACT Background International health research collaborations (IHRCs) between High Income countries (HICs) and Low‐and Middle‐Income Countries (LMICs) are essential in global health research, yet ethical challenges including the inequitable sharing of rewards and burdens among the research actors remain insufficiently addressed.
George Kwasi Barimah   +4 more
wiley   +1 more source

Sensor‐Detected Hypoglycaemia Is Associated With Inflammatory Protein and Immune Cell Alterations in People With Diabetes: Findings From the Hypo‐METRICS Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Experimental hypoglycaemia induces a persistent inflammatory response. We investigated whether real‐life sensor‐detected hypoglycaemia (SDH) is associated with immune parameters in people with Type 1 and Type 2 diabetes and explored potential differences between the groups.
Mandala Ajie   +15 more
wiley   +1 more source

The mortality gradient in town and country: Social class and childhood mortality in Sweden at the turn of the twentieth century

open access: yesThe Economic History Review, EarlyView.
Abstract This study examines social‐class and urban–rural differentials in childhood mortality in Sweden from 1880 to 1910, a period of steady mortality decline, ongoing industrialization, and urbanization. Urbanization brought improvements in water quality and sanitation but also increased risks from overcrowding, pollution, and infectious diseases ...
Marcos Castillo, Martin Dribe
wiley   +1 more source

Airflow constraints govern natural airborne transmission of tuberculosis. [PDF]

open access: yesmSphere
Naqvi KF   +13 more
europepmc   +1 more source

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