Results 101 to 110 of about 709,968 (295)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

De bestias sobrenaturales a fauna de la naturaleza: las especies animales, su significación y su relación con el individuo a la luz de la expansión del siglo XII en Santiago de Compostela

Ítaca
El artículo toma como centro la consideración de las especies animales y la relación que mantienen con las poblaciones e individuos para reinterpretar su significación en una perspectiva nueva: la de los cambios sociales y económicos de la expansión de ...
Xosé M. Sánchez Sánchez
doaj   +1 more source

Animales, animales y más animales

, 2008
ESP
openaire   +1 more source

Tijeretas, animales sorprendentes [PDF]

, 2015
Peer ...
García-París, Mario
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

La antropomorfización del vínculo humano-animal en las dinámicas familiares: una revisión documental

Pensamiento Americano
Introducción: El estudio de la interacción entre humanos y animales de compañía ha cobrado relevancia debido a los cambios en las dinámicas sociales actuales.
Maria Cristina Correa Duque, Anyerson Stiths Gómez Tabares, Valentina Posada Hoyos   +2 more
doaj   +1 more source

Architectures animales

Histoire de l'art, 2001
Building for animals. If Historians have, for a long time, underlined and studied the plentiful presence of animals in architecture, they paid less attention, at least in France, to the buildings for animals. This article deals with the present state of studies and new possibilities from examples concerning animals : zoological gardens and circus
openaire   +3 more sources

INTRODUCCIÓN A LOS SISTEMAS ANIMALES [PDF]

, 2017
SÓLO VISIÓN ...
SANCHEZ SANCHEZ HERMILO
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Constructivismo, contractualismo y teoría política animal

Ideas y Valores
El objetivo del trabajo es contribuir a las discusiones metateóricas y metodológicas que se están desarrollando en el contexto del giro político de la ética animal.
Pedro Riquelme Peña
doaj