Results 111 to 120 of about 122,873 (307)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Derechos de los animales y deberes de justicia

, 2019
La defensa de derechos para los animales es promovida por Regan. Su enfoque de los derechos está basado en asignar un valor inherente a todo sujeto-de-una-vida, es decir, se enmarca en la idea de defender un estatus moral a partir de una categoría ...
Ocampo Giraldo, Rodrigo Jesús
core   +1 more source

Uso de animales de experimentación en la investigación biomédica en Costa Rica Using Experimental Animal in Biomedical Research in Costa Rica

Acta Médica Costarricense, 2010
El progreso en la investigación médica y biológica ha dependido en gran medida del uso de animales experimentales Dada la importancia que históricamente han tenido los animales como reactivos biológicos en la investigación biomédica se consolidó la ...
Jorge Granados-Zúñiga
doaj  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Destruction des farines animales : Valorisation des fractions lipidiques en biolubrifiants et additifs biocarburants, et du résidu protéique (ou de l’ensemble) pour la fabrication de matériaux polymères [PDF]

, 2004
L’objectif des travaux est d’étudier la faisabilité de nouvelles voies d’élimination et de valorisation des farines animales. Nous abordons ici l’étude de deux voies de valorisation complémentaires et indépendantes : d’une part, la valorisation de ...
Mouloungui, Zephirin,, Mouloungui, Zéphirin, Lacroux, Eric, Vaca-Garcia, Carlos, Peydecastaing, Jérôme   +4 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

La custodia de los animales de compañía en la Ley 17/2021

, 2023
El presente trabajo tiene como finalidad analizar la determinación de la custodia de los animales de compañía, en función de los cambios implementados por el legislador en la Ley 17/2021, que se encuentran en vigencia desde el año 2022.
Clavijo Suntura, Joel Harry
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Chinampas de Xochimilco: un sistema agrosilvopastoril ancestral

AIA Avances en Investigación Agropecuaria
Introducción. Las chinampas (Ch) de Xochimilco son un sistema agroecológico milenario que integra conocimiento tradicional, alta biodiversidad, producción pecuaria y prácticas sostenibles; modelo que enfrenta la crisis climática, la urbanización y la ...
Daniel Luna Hernández, Gretel Iliana Gil González, José Manuel Palma García   +2 more
doaj   +1 more source