Results 181 to 190 of about 3,673,245 (381)
FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui +15 more
wiley +1 more source
The variation of animals and plants under domestication
, 1897 Charles Darwin
openalex +2 more sources
FEBS Open Bio, EarlyView.Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei +7 more
wiley +1 more source
Pastor.i: a smartphone application to facilitate grazing management [PDF]
, 2018 Grazing in extensive beef farming systems is often manage in an empirical way based on past experience and on the visual appreciation of animal behavior and forage potential. Records of entrances and exits of the animals in the paddocks are rare. However,
Cancela d'Abreu, Manuel +4 more
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FEBS Open Bio, EarlyView.Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee +5 more
wiley +1 more source
Science and Faith; Or, Man as an Animal and Man as a Member of Society. Paul Topinard , Thomas J. McCormack [PDF]
, 1900 Wendell Thomas
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FEBS Open Bio, EarlyView.ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu +6 more
wiley +1 more source
Nutrición y alimentación de rumiantes jóvenes [PDF]
, 2015 Los animales jóvenes representan uno de los mayores problemas de las explotaciones comerciales, puesto que es en este momento cuando se deben sentar las bases para un correcto crecimiento y es, a su vez, cuando más delicados son todos los animales en ...
Bacha, Fernando +1 more
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