Results 31 to 40 of about 122,873 (307)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Fantasía y razón en Margaret Cavendish. O acerca del conocimiento de animales, vegetales y minerales
DaimonResumen: Este artículo tiene como objetivo estudiar las nociones de fantasía y razón en dos obras de Margaret Cavendish: Fantasías filosóficas (1653) y Philosophicall Letters (Cartas filosóficas, 1664).
Claudia Aguilar
doaj +1 more source
Raigal, 2022 El objetivo de este artículo es interpretar desde categorías de la semiótica peirceana la función de los signos de la animalidad en dos escenas de la discursividad política reciente.
Pablo Daniel Sánchez Ceci
doaj
De la razón cordial a la compasión: La ética con los animales
Revista Latinoamericana de Bioética, 2015 Este artículo discute la siguiente tesis: la ética (responsabilidad consigo mismo, con los animales, con el entorno) se basa en la compasión, progresivamente dilucidada por sucesivos estados mentales de segundo orden.
Teresa Arbeláez Cardona +1 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Los animales enamorados en la tradición oral andina: el caso de un gusano y una joven
DesafíosObjetivo. Exponer las características de los personajes (animal seductor y doncella engañada), así como el significado simbólico que tanto estos como las situaciones que atraviesan representan en el imaginario del runa, a partir de la serie de relatos ...
Timna Yulisa Huamán Antonio
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source