Results 111 to 120 of about 685 (301)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
What Does it Mean to Say That We Are Animals? [PDF]
, 2015 The view that we are animals -- animalism -- is often mis-understood. It is typically stated in unhelpful or misleading ways. Debates over animalism are often unclear about what question it purports to answer, and what the alternative answers are.
Olson, E.T.
core
Anthropocentrism, Natural Harmony, Sentience and Animal Rights: Are We Allowed to Use Animals for Our Own Purposes? [PDF]
Animals (Basel), 2023 Pulina G.
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Animalism, the thinking animal and the ancestry of persons
, 2019 The debate on personal identity in philosophy is about what makes a person at one point intime the same person as a person at another point in time. Animalism is a point of view whichhas it that being the same human animal is what makes a person at one ...
Larsson, Kim
core
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Effects of blood meal sources on the biological characteristics of Aedes aegypti and Culex pipiens (Diptera: Culicidae). [PDF]
Saudi J Biol Sci, 2022 Al-Rashidi HS +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The needs analysis of the marriage education program for Turkish Cypriot community: Development phase. [PDF]
Front Psychol, 2022 Salman N, Batman KA, Sorakin Y.
europepmc +1 more source