Results 81 to 90 of about 685 (301)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

<サーヴェイ論文>私たちとは何であるか : 動物説と構成主義 [PDF]

open access: yes, 2019
In personal ontology, animalism and constitutionalism are rival answers to the metaphysical question "What are we?" or "What is our nature?" Roughly, animalism says that we are biological animals, while constitutionalism says that we are not identical to
横路, 佳幸
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Personalism vs. animalism: a phenomenological argument [PDF]

open access: yes, 2020
Se ha dado por sentado, a lo largo de los siglos, la superioridad de los seres humanos sobre la especie animal alegando a la racionalidad y la libertad que hace de las personas sujetos de derechos y deberes. No obstante, hoy en día, en el contexto de
Martínez Mares, Miriam
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Animalism and the Human Perspective

open access: yes, 2016
What are we? What can we survive? According to animalism, we are animals, and so can survive whatever the animals that we are can survive. I argue that animalism ought to be considered a default view, before turning a critical eye towards certain ...
Geddes, AL
core  

We Are All Loose and Popular. An Argument in Support of Loose and Popular Identity

open access: yesOstium, 2020
Joseph Butler stated that identity can be seen in two ways: a loose and popular one, and a strict and philosophical one. In this paper I will argue that every identity must be seen in the former since it is impossible to have identity in a strict and ...
Lasse Nielsen
doaj  

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Animalism in Macedonian literature for children [PDF]

open access: yes, 2016
Animals have always had their place in literature. Primitive storytellers have used animals to make dramatic human daily struggle against the forces of nature. The man from time immemorial been associated with wildlife. In prehistoric times he hunted and
Denkova, Jovanka
core  

“Those who suffer the ecstasy of the animals”. Conceptual Blending and Eco-animalism in Atwood’s Speculative Fiction

open access: yes, 2015
This paper takes as its starting point the notions of blending and conceptual metaphors in order to advance a new reading of Atwood’s fiction, one which sees it as parabolic stories projecting the conceptual metaphors “man is a wild animal” and ...
SASSO, Eleonora
core   +1 more source

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