Results 41 to 50 of about 15,188 (291)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Confused Robots and Incompetent Humans in Jean-Pierre Jeunet’s Bigbug (2022)

open access: yesAlternative Francophone
Jean-Pierre Jeunet has been working on the presentation of struggling human bodies, in his films such as Delicatessen (1991), La Cité des enfants perdus/The City of Lost Children (1995), and most recently, Bigbug (2022).
Hyunjin Kim
doaj   +1 more source

Pojken med koskällan och tjuren på Nybacken

open access: yesTidskrift för Litteraturvetenskap, 2019
The Boy with the Cowbell & The Bull of Nybacken: A Queer Reading of Vilhelm Moberg’s The Emigrants Novels This article presents a queer reading of Vilhelm Moberg’s The Emigrants novel series (1949–1959), in which norm-breaking aspects of the text are
Oscar von Seth
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

On Laruelle and the Radical Dyad: Katerina Kolozova's Materialist Non-Humanism [PDF]

open access: yes, 2019
As one of the seminal theorists further developing François Laruelle’s politically-poised “non-standard philosophy,” Katerina Kolozova’s approach to animality and feminism is part of a particular post-humanist Marxist continuum (which includes Rosi ...
Erkan, Ekin
core  

" Animal, trop animal " [PDF]

open access: yesLe Portique, 2009
Dans la tradition philosophique, on trouve plusieurs definitions de l’homme. La celebre definition aristotelicienne, zoon logon echon (animal doue du langage ou animal rationnel) fournit le paradigme ainsi que la methode de toutes les definitions successives.
openaire   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Autoimmunity and the Irony of Self-Definition: Translating the Economy of Terror

open access: yesSanglap: Journal of Literary and Cultural Inquiry, 2014
In order to avoid descending into the state of nature the sovereign takes over the appearance of the state of nature itself – the animality that is primordial to the constitution of this legal framework, the animality of primitive force.
Samrat Sengupta
doaj  

Tracing the Animal in the Human

open access: yesHumanimalia, 2015
Christopher Peterson. Bestial Traces: Race, Sexuality, Animality. New York: Fordham University Press, 2013. 208 pp. $75 hc, $24 pb.
Chloe Diamond-Lenow
doaj   +1 more source

Neither Animal nor Human: An Ecogothic reading of the Monstrous Hybrid in Dracula, The Beetle and The Snake Lady

open access: yesPangeas, 2020
This article analyses the relationship between humans and animals, and more importantly between humans and their animality. Concretely, this project proposes an ecocritical reading of fin de siècle gothic fiction, as it provides insight on the ...
Aurora Murga Aroca
doaj   +1 more source

Home - About - Disclaimer - Privacy