Results 91 to 100 of about 7,438,473 (359)
, 2020 The article presents a historical development path of the Laboratory of biochemistry of adaptation and ontogenesis of animals which began with the founding of the Ukrainian Research Institute of Physiology and Biochemistry of Farm Animals in 1960. At the
H. V. Klymets +2 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The ‘R’ principles in laboratory animal experiments
Laboratory Animal Research, 2020 Since the Three Rs of replacement, reduction and refinement was proposed by Russel and Birch in 1959, researchers have a moral duty to minimize harm to animals. Even though animal experiments are performed by the Three Rs concept, animal researches which
K. Lee, Dong Woon Lee, Byeong-Chul Kang
semanticscholar +1 more source
Bioresource collections of laboratory animals
Вавиловский журнал генетики и селекции, 2017 .
M. P. Moshkin
doaj
, 2013 The primary aim of this report is to assist scientists in selecting more reliable/suitable identification (ID) methods for their studies. This is especially true for genetically altered (GA) animals where individual identification is strictly necessary ...
Sveriges lantbruksuniversitet. +2 more
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Statistical design for health monitoring in laboratory animal facilities using sentinel animals
Regular health monitoring is crucial in laboratory animal facilities to determine the presence or absence of specific pathogens. One common approach to monitoring involves the use of sentinel animals, which are periodically exposed to biological material
Sorzano, Carlos Oscar S +2 more
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
An Estimate of the Number of Animals Used for Scientific Purposes Worldwide in 2015
Alternatives to laboratory animals : ATLA, 2019 Few attempts have been made to estimate the global use of animals in experiments, since our own estimated figure of 115.2 million animals for the year 2005. Here, we provide an update for the year 2015.
Katy Taylor, L. R. Alvarez
semanticscholar +1 more source
Anesthesia and analgesia in laboratory animals /
, 1997 Anesthesia and Analgesia in Laboratory Animals focuses entirely on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery.
Kohn, Dennis F.
core