Results 81 to 90 of about 5,412,710 (314)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Economic Impacts of Vertebrate Pests in Australia
Invasive animal pests have a wide variety of impacts on the economy, the environment and society. There is considerable information on these impacts for individual cases and regions, and McLeod (2004) attempted to value them nationwide for a whole range ...
Sinden, Jack A +5 more
core
Chlamydia (Chlamydophila) pneumoniae in animals: a review
An important discovery in the last couple of years is that humans are not the only natural hosts with which C. pneumoniae is the primary cause for the disease. Successively, the C.
L. Pospisil, J. Canderle
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Blood Sampling from Laboratory Rabbits
Background: Proper method of blood collection (BC) has significant consequences in many biological productions and research activities. Due to the challenges of blood collection from laboratory rabbits, cardiac puncture is routinely performed as the ...
Siavash Ahmadi-Noorbakhsh +1 more
doaj
The Guangdong Province Laboratory Animals Ordinance (the GPLAO), officially enacted and implemented in October 2010, marked a new phase of legal management in the administration of laboratory animals in Guangdong Province.
DENG Shaochang +5 more
doaj +1 more source
Forensic luminol reaction for detecting fecal occult blood in experimental mice
Fecal occult blood (FOB) is a sign of gastrointestinal diseases, such as intestinal ulcers and colorectal cancer. In experimental animal studies, there is no standard method to detect FOB.
Ah-Mee Park, Ikuo Tsunoda
doaj +1 more source

