Results 201 to 210 of about 6,610,213 (244)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Comparison of Antigen Conjugation to a Peptidic Carrier or to Bovine Serum Albumin in the Serodiagnosis of Canine Visceral Leishmaniasis via Suspension Array Technology. [PDF]

Antibodies (Basel)
Toledo TS, Cunha PM, Lima-Junior JDC, De Campos MP, Renzetti ARS, Figueiredo FB, Morgado FN, Porrozzi R, Conceição-Silva FD, Santiago MA, De Luca PM.   +10 more
europepmc   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Evaluating the Biochemical and Haematological Safety of the Histoplasma capsulatum var. farciminosum '8ZH' Vaccine in Foals. [PDF]

Vet Med Sci
Alpysbayeva SE, Abdykalyk AA, Tileukhanov K, Abdimukhtar AR, Toleukhan AT, Sarmykova MK, Anarbekova AM, Shayakhmetov YA, Syrym NS, Nurabaev SS, Yespembetov BA.   +10 more
europepmc   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

A survey on the implementation of environmental health monitoring in mouse facilities in German-speaking countries. [PDF]

PLoS One
Mahabir E, Schmidt K, Kolbe T, Buchheister S, Miller M.   +4 more
europepmc   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Optimizing Nucleic Acid Extraction from Extended Bovine Semen for Endemic and High-Consequence Pathogens. [PDF]

Animals (Basel)
Zimmerman A, Vandenburg-Carroll A, Marthaler DG, Lim A.   +3 more
europepmc   +1 more source

Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong, Min‐Hee Lee, Hiroshi Uda, Yoon Ho Hwang, Michael Behen, Aimee Luat, Csaba Juhász, Eishi Asano   +7 more
wiley   +1 more source

Metalog: curated and harmonised contextual data for global metagenomics samples. [PDF]

Nucleic Acids Res
Kuhn M, Schmidt TSB, Ferretti P, Głazek A, Robbani SM, Akanni W, Fullam A, Schudoma C, Cetin E, Hassan M, Noack K, Schwarz A, Thielemann R, Thomas L, von Stetten M, Alves R, Iyappan A, Kartal E, Kel I, Keller MI, Maistrenko O, Mankowski A, Nishijima S, Podlesny D, Schiller J, Schulz S, Van Rossum T, Bork P.   +27 more
europepmc   +1 more source