Results 31 to 40 of about 6,610,213 (244)
Alternatives to laboratory animals : ATLA, 2018 Recurrent acute and/or chronic stress can affect all vertebrate species, and can have serious consequences. It is increasingly and widely appreciated that laboratory animals experience significant and repeated stress, which is unavoidable and is caused ...
Jarrod Bailey
semanticscholar +1 more source
Effects of Light at Night on Laboratory Animals and Research Outcomes
Behavioral Neuroscience, 2018 Light has substantial influences on the physiology and behavior of most laboratory animals. As such, lighting conditions within animal rooms are potentially significant and often underappreciated variables within experiments. Disruption of the light/dark
Kathryn M. Emmer +4 more
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Alternatives to Carbon Dioxide—Taking Responsibility for Humanely Ending the Life of Animals
Animals, 2019 Carbon dioxide (CO2) is commonly used to kill rodents. However, a large body of research has now established that CO2 is aversive to them. A multidisciplinary symposium organized by the Swiss Federal Food Safety and Veterinary Office discussed the ...
Shannon Axiak Flammer +8 more
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General Anesthetics Commonly Used for Laboratory Animals
Shiyan dongwu yu bijiao yixue, 2022 General anesthetics used for laboratory animals are mostly controlled drugs, and are subject to strict supervision by the competent government agency in China.
LU Xiao +5 more
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State of the art in vivo imaging techniques for laboratory animals
Laboratory Animals. Journal of the Laboratory Animal Science Association, 2017 In recent decades, imaging devices have become indispensable tools in the basic sciences, in preclinical research and in modern drug development. The rapidly evolving high-resolution in vivo imaging technologies provide a unique opportunity for studying ...
David Tibor Lauber +5 more
semanticscholar +1 more source
Veterinary Medicine International, 2015 This study was to establish a systemic C. parapsilosis infection model in immunosuppressed ICR mice induced by cyclophosphamide and evaluate the antifungal efficiency of fluconazole. Three experiments were set to confirm the optimal infectious dose of C.
Yu’e Wu +7 more
doaj +1 more source
PLoS ONE, 2016 Scientists who perform major survival surgery on laboratory animals face a dual welfare and methodological challenge: how to choose surgical anesthetics and post-operative analgesics that will best control animal suffering, knowing that both pain and the
L. Carbone, Jamie Austin
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser +6 more
wiley +1 more source
Biology Open, 2016 Tumor necrosis factor alpha (TNFα) plays a key role in the pathogenesis of rheumatoid arthritis (RA). Blockade of TNFα by monoclonal antibody has been widely used for the therapy of RA since the 1990s; however, its mechanism of efficacy, and potential ...
Ge Li +6 more
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Health Monitoring of Laboratory Rodent Colonies—Talking about (R)evolution
Animals, 2021 Simple Summary When working with laboratory animals, scientists need to ensure that animals are not suffering from natural infections. Therefore, hygienic standards have been developed over the last 100+ years. The key element of hygienic standardization
Stephanie Buchheister, A. Bleich
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