Results 251 to 260 of about 244,970 (309)

Intergenerational and organ-specific alterations in mitochondrial DNA copy number following preconception irradiation. [PDF]

Redox Biol
Seino R, Fukunaga H.
europepmc   +1 more source

Impact of chronic cold stress on metabolism, colostrum quality, and lamb performance in locally adapted ewes. [PDF]

Trop Anim Health Prod
Uysal A, Yılmaz E, Gür C, Uysal S, Türkyılmaz D, Türkyılmaz ÜD.   +5 more
europepmc   +1 more source

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Acute toxicity of drugs in newborn animals

The Journal of Pediatrics, 1966
The acute toxicities of 30 compounds were compared in 1- to 3-day-old and adult(150 gram) rats. The effect of maturation on acute toxicity was generally consistent within a pharmacologic class of compounds. Only 16 of the 30 compounds were particularly more toxic to the newborn rat. The central nervous system depressants were more toxic in the immature
R A, Yeary, R A, Benish, M, Finkelstein
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Chemical sympathectomy in newborn animals

Neuropharmacology, 1971
Abstract Treatment of newborn mice and rats with 6-hydroxydopamine caused the massive destruction of all sympathetic ganglia. Morphological and biochemical evidence show that the sympathectomy obtained with this method is complete and persists up to 6 months after treatment.
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Myocardial function in the newborn animal

The Journal of Pediatrics, 1964
The roles of hypoxia and hypercapnia in elevating pulmonary arterial pressure and resistance were evaluated in normal unanesthetized newborn lambs. Nineteen Iambs without ductus shunting were studied in room air 4 hours to 10 days after birth with blood gases, pH, pulmonary, systemic, and atrial pressures, and indicator dilution cardiac output ...
Norman S. Talner, Thomas H. Gardner, S. Evans Downing   +2 more
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Chest compressions in newborn animal models: A review

Resuscitation, 2015
Much of the knowledge about the optimal way to perform chest compressions (CC) in newborn infants is derived from animal studies. The objective of this review was to identify studies of CC in newborn term animal models and review the evidence. We also provide an overview of the different models.MEDLINE, EMBASE and CINAHL, until September 29th 2014 ...
Anne Lee, Solevåg, Po-Yin, Cheung, Helene, Lie, Megan, O'Reilly, Khalid, Aziz, Britt, Nakstad, Georg Marcus, Schmölzer   +6 more
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Diazepam metabolism and anticonvulsant activity in newborn animals

Biochemical Pharmacology, 1973
Abstract Diazepam metabolism was studied in vivo and in vitro in newborn and adult rats and guinea-pigs. Both newborn rats and guinea-pigs are more sensitive to the antimetrazol action of diazepam than the adult animals. The difference in activity was about fifteen times for rats but only twice for guinea-pigs.
F, Marcucci, E, Mussini, L, Airoldi, A, Guaitani, S, Garattini   +4 more
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Acquired tolerance of foreign cells in newborn animals

Proceedings of the Royal Society of London. Series B - Biological Sciences, 1956
Acquired tolerance of skin homografts may be brought about experimentally by the introduction of the antigenic stimulus, in the form of living homologous tissue cells, into the embryo before its immunological defence mechanism has become functionally mature (Billingham, Brent & Medawar 1953, 1956). In practice, this may be accomplished
R E, BILLINGHAM, L, BRENT
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Biotransformation and Pharmacokinetics of Salicylate in Newborn Animals

American Journal of Veterinary Research, 1973
SUMMARY Plasma half-lives and urinary metabolites were examined in pups, kids, pigs, and a foal after intravenous administration of sodium salicylate (44 mg./kg.). Each subject was studied at 1 day of age and periodically to 30 days. The plasma half-lives of salicylate decreased as a function of age.
L E, Davis, B A, Westfall, C R, Short
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