Results 31 to 40 of about 1,457,674 (303)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Pathologie associée à une carence en vitamine A dans une ferme laitière marocaine [PDF]
Clinical signs associated with vitamin A deficiency in a Moroccan dairy farm. In a dairy farm of the Temara area (Morocco) various observed clinical manifestations were suggestive of vitamin A deficiency.
Mahin, L., Dewulf, M., Lakhdissi, H.
doaj
Bioaerosol, particulate matter concentration and antibiotic resistance of airborne Staphylococcus was assessed in animal and public premises (classroom, sports hall, horse stable, cowshed, newborn calf shed and outdoor background control site) of Poland ...
Anna Lenart-Boroń +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Genetically altered stable non reverting aromatic dependent (aro) Salmonella typhimurium,strain SL1479 was administrated intramuscularly to healthy pregnant guinea pigs as alive vaccine.
Yousif A. A.
doaj +1 more source
Pathological anxiety in animals [PDF]
selective breeding programmes in domestic and laboratory animals generally focus on physiological and/or anatomical characteristics. However, selection may have an (unintended) impact on other characteristics and may lead to dysfunctional behaviour that ...
Dep Gezondheidszorg Landbouwhuisdieren +6 more
core +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
New techniques for producing transgenic animals - a mixed blessing from both the scientific and animal welfare perspectives [PDF]
A further increase in the use of genetically-modified animals will be against the European Union policy to move away from the use of animals in biomedical ...
Algemeen Onderzoek DGK +3 more
core +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
When and How Do Children Start Producing A Languge?
This article discusses how a child speaks his first language. The first language spoken through several phases is called the semantic process, syntax and phonology. Newborn babies get their first language from their mother called mother tongue.
Musliadi Musliadi
doaj +1 more source

