Results 121 to 130 of about 1,122,045 (313)

Molecular characterization of Cryptosporidium spp. from wild rats and mice from rural communities in the Philippines

, 2013
In order to examine the prevalence of Cryptosporidium in wild rodents in the Philippines and understand the role wild rodents play in the transmission of this parasite to humans and livestock, 194 fecal samples from wild rats and mice from Luzon and ...
Ng-Hublin, J.S.Y., Singleton, G.R., Ryan, U.   +2 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

First report of the giant liver fluke (Fascioloides magna) in Slovenia and molecular species confirmation based on the ITS2 marker

Frontiers in Veterinary Science
IntroductionThe giant liver fluke, Fascioloides magna, is a parasite that primarily infects wild and domestic ruminants. Originally from North America, it has been an invasive species in Europe since the nineteenth century. Of the three natural foci that
Diana Žele Vengušt, Darja Kušar, Gorazd Vengušt, Petra Bandelj   +3 more
doaj   +1 more source

The vocalisations and anti-predatory behaviour of wild white-handed gibbons (Hylobates lar) in Khao Yai National Park, Thailand

, 2011
The loud songs of gibbons (Hylobatidae) usually consist of a duet by the mated pair delivered each morning. These songs can transmit over a kilometre through dense forest habitat and therefore presumably play a role in long-distance communication.
Clarke, Esther A. E.
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Case report: First report of potentially zoonotic Gongylonema pulchrum in a free-living roe deer (Capreolus capreolus) in Slovenia

Frontiers in Veterinary Science
Adult female and male Gongylonema nematodes were found in the oesophagus of a free-living roe deer (Capreolus capreolus) in Slovenia during passive health surveillance of wildlife.
Petra Bandelj, Diana Žele Vengušt, Gorazd Vengušt, Darja Kušar   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Genomic revelations: investigating rotavirus a presence in wild ruminants and its zoonotic potential

Frontiers in Veterinary Science
IntroductionRotaviruses A (RVA) are a major cause of acute viral gastroenteritis in humans worldwide and are responsible for about two million hospitalizations per year.
Petra Šenica, Diana Žele Vengušt, Gorazd Vengušt, Urška Kuhar   +3 more
doaj   +1 more source

Wild animals I have known : and 200 drawings

, 1898
Mode of access ...
Seton, Ernest Thompson, 1860-1946, Ernest Thompson Seton, Seton, Ernest Thompson, 1860-1946.   +2 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source