Results 121 to 130 of about 3,008,330 (304)

First report of the giant liver fluke (Fascioloides magna) in Slovenia and molecular species confirmation based on the ITS2 marker

Frontiers in Veterinary Science
IntroductionThe giant liver fluke, Fascioloides magna, is a parasite that primarily infects wild and domestic ruminants. Originally from North America, it has been an invasive species in Europe since the nineteenth century. Of the three natural foci that
Diana Žele Vengušt, Darja Kušar, Gorazd Vengušt, Petra Bandelj   +3 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Case report: First report of potentially zoonotic Gongylonema pulchrum in a free-living roe deer (Capreolus capreolus) in Slovenia

Frontiers in Veterinary Science
Adult female and male Gongylonema nematodes were found in the oesophagus of a free-living roe deer (Capreolus capreolus) in Slovenia during passive health surveillance of wildlife.
Petra Bandelj, Diana Žele Vengušt, Gorazd Vengušt, Darja Kušar   +3 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Decellularized Rat Lung Extracellular Matrix as an In Vitro Platform for Canine Yolk Sac–Derived Endothelial Precursor Cells for Pulmonary Endothelium Reconstruction Studies

Bioengineering
Pulmonary bioengineering holds significant promise for the development of functional lungs suitable for transplantation in patients with terminal lung diseases; however, it encounters considerable challenges.
Leandro Norberto da Silva-Júnior, Maria Angelica Miglino, Bianca de Oliveira Horvath-Pereira, João Victor Barbosa Tenório Fireman, Giovanna Macedo da Siqueira, Maria Laura dos Reis Ferre Pereira, Letícia dos Santos Bezerra, Luís Vicente Franco de Oliveira, Samuel de Sousa Morais, Márcia Zilioli Bellini, Carlos Henrique Bertoni Reis, Rogerio Leone Buchaim, Daniela Vieira Buchaim   +12 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Comparative study and geographical distribution of key protected wild vascular plants in Jiangxi Province, China

Guangxi Zhiwu
Rare and endangered wild plants are important strategic resources and an essential component of biodiversity conservation. Grasping the diversity and geographic distribution of key protected plants in Jiangxi Province is a key step in developing ...
WAN Pingping1, WANG Lisong1*, WU Shaodong1, XIE Minghua2
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

First report of melanophoroma in Salvator merianae

Brazilian Journal of Veterinary Pathology
Cutaneous neoplasms have been described in the class Reptilia, and many of them are related to the inadequate management of these animals in captivity.
Sofia Silva La Rocca de Freitas, Lucas de Paula Pereira, Maria Estela Mendes da Silva, Karina Harumi Chinen, Márcio de Barros Bandarra   +4 more
doaj   +1 more source