Results 201 to 210 of about 3,008,330 (304)
Easy rescues, difficult decisions: Advancing the ethical dialogue in wildlife triage, treatment and rehabilitation. [PDF]
Campbell-Ward M +3 more
europepmc +1 more source
Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu +7 more
wiley +1 more source
Unknown Biases: Understanding How Anthropogenic Hybridization Impacts Genomic Diversity and Demographic Estimates. [PDF]
Hernández F, Lavretsky P.
europepmc +1 more source
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen +20 more
wiley +1 more source
Molecular Survey of <i>Trypanosoma</i>, <i>Babesia</i> and <i>Theileria</i> Infections in Major Livestock and Rodents in Xinjiang, Northwestern China. [PDF]
Li Y +9 more
europepmc +1 more source
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan +17 more
wiley +1 more source
Reptiles & amphibians : based on the television series, Wild, wild world of animals.
Oulahan, Richard
core
Blood parameters of wild-caught harbor seals (<i>Phoca vitulina</i>) in the German North Sea: reference intervals and potential influencing factors. [PDF]
Gross S, Ruser A, Siebert U.
europepmc +1 more source

