Results 181 to 190 of about 1,122,045 (313)

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats

open access: yesAdvanced Functional Materials, EarlyView.
We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang   +18 more
wiley   +1 more source

Stochastic growth and ligand-receptor interaction-mediated stabilization generate stereotyped dendritic arbors. [PDF]

open access: yesNat Neurosci
Shi R   +10 more
europepmc   +1 more source

Multimodal Perception and Machine Learning‐Empowered Human Machine Interfaces With Double‐Network Hydrogel Fibers

open access: yesAdvanced Functional Materials, EarlyView.
This work develops polyacrylamide‐alginate (PAM‐Alg) double‐network hydrogel fibers for multimodal perception and intelligent human‐machine interfaces. The covalent‐ionic network provides high strength, toughness, and stable conductivity. Easily woven into wearables and integrated with soft robots, the fibers enable object and temperature recognitions ...
Yujue Yang   +10 more
wiley   +1 more source

A Molecular Shielding Strategy to Develop Low Protein Binding, Renal Clearable Pan‐Cancer Near‐Infrared Probes

open access: yesAdvanced Functional Materials, EarlyView.
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang   +9 more
wiley   +1 more source

<i>CD1D</i> knockout swine are permissive to African swine fever virus genotype II infection. [PDF]

open access: yesEmerg Microbes Infect
Madden D   +15 more
europepmc   +1 more source

Data visualization : Common carriers of rabies by location in the US

open access: yes
In 1938, most cases of rabid animals reported were domestic (9,321) and some were wild (44). Since then, the numbers have reversed. In 2017, 399 cases of rabid animals reported were domestic and 4,055 were wild.vs-rabies-infographic1 ...

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