Results 261 to 270 of about 8,895,509 (405)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Exploring human-animal interactions beyond academic research: A rapid review of grey literature. [PDF]
Ru S+3 more
europepmc +1 more source
XIX.—On some of the animals of the Chemnitziæ which have not been described [PDF]
William Clark
openalex +1 more source
Environmentally induced oxidative stress in aquatic animals.
V. Lushchak
semanticscholar +1 more source
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
Novel Bunyavirus in Domestic and Captive Farmed Animals, Minnesota, USA
Zheng Xing, Michael Murtaugh
doaj +1 more source
Detection of Antibodies Against Leptospira interrogans Serovars Among Stabled Horses in Qazvin Province of Iran as a One-Health Concern. [PDF]
Imandar M+10 more
europepmc +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
NR1I3 modulates Wnt signaling to promote anterior-posterior axis patterning. [PDF]
Sun Y+7 more
europepmc +1 more source