Results 61 to 70 of about 6,377,049 (337)

Bestiary Images of Federigo Tozzi (Beasts and With Closed Eyes) [PDF]

open access: yesStudia Litterarum
Observation of animals in the works of Federigo Tozzi, one of the greatest modernist writers in 20th-century Italian literature, primarily holds ontological significance.
Liudmila E. Saburova
doaj   +1 more source

Animals and Objectivity [PDF]

open access: yes, 2020
Starting from the assumption that Kant allows for the possible existence of conscious sensory states in non-rational animals, I examine the textual and philosophical grounds for his acceptance of the possibility that such ...
McLear, Colin
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Figurations of Alterity: an Encounter with the Archive

open access: yesGlocalism: Journal of Culture, Politics and Innovation, 2021
In this work I ponder about the archive based on three images from the late nineteenth and early twentieth centuries: the drawing of a monster from the Teratology collection of the Museo Nacional de México preserved today in the Biblioteca Nacional de ...
Frida Gorbach
doaj  

Cinematic slowness, political paralysis? Animal life in ‘Bovines’, with Deleuze and Guattari

open access: yesNECSUS, 2015
Deleuze elaborates accounts of cinematic time and of becoming-animal quite separately, without addressing potential links between these accounts. Drawing on a range of works by Deleuze and Guattari, this article allows these accounts to intersect ...
Laura McMahon
doaj   +1 more source

Standardized nuclear markers improve and homogenize species delimitation in Metazoa

open access: yesMethods in Ecology and Evolution, 2023
Species are the fundamental units of life and evolution. Their recognition is essential for science and society. Molecular methods have been increasingly used for the identification of animal species, despite several challenges.
Lars Dietz   +16 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Forensic luminol reaction for detecting fecal occult blood in experimental mice

open access: yesBioTechniques, 2018
Fecal occult blood (FOB) is a sign of gastrointestinal diseases, such as intestinal ulcers and colorectal cancer. In experimental animal studies, there is no standard method to detect FOB.
Ah-Mee Park, Ikuo Tsunoda
doaj   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

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