Results 81 to 90 of about 8,895,509 (405)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Serum proteins and their diagnostic utility in veterinary medicine: a review
Veterinární Medicína, 2016 The evaluation of serum proteins and their electrophoretic pattern is a well-established laboratory method in the diagnosis of many diseases in humans, which has replaced the biochemical determination of the concentrations of albumin and the ratio of ...
C. Tothova, O. Nagy, G. Kovac
doaj +1 more source
Onderstepoort Journal of Veterinary Research, 2022 Historically, the use of antibiotics was not well regulated in veterinary medicine. The emergence of antibiotic resistance (ABR) in pathogenic bacteria in human and veterinary medicine has driven the need for greater antibiotic stewardship.
Jeanette M. Wentzel +2 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Animals as Neighbours: The Past and Present of Commensal Animals by Terry O\u27Connor [PDF]
, 2015 Review of Terry O\u27Connor\u27s Animals as Neighbours: The Past and Present of Commensal ...
Woods, Derek
core +1 more source
Global trends in antimicrobial resistance in animals in low- and middle-income countries
Science, 2019 Livestock antibiotic resistance Most antibiotic use is for livestock, and it is growing with the increase in global demand for meat. It is unclear what the increase in demand for antibiotics means for the occurrence of drug resistance in animals and risk
T. V. Van Boeckel +8 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Animals in Christian and Muslim Thought [PDF]
, 2018 In this chapter, I shall offer a comparative exegesis and critical assessment of the Christian and Muslim views of animals. This chapter is divided into three parts.
Frayne, Carl Tobias
core
The genomes and history of domestic animals [PDF]
, 2016 This paper reviews how mammalian genomes are utilized in modern genetics for the detection of genes and polymorphisms (mutations) within domesticated animal (mostly livestock) genomes that are related to traits of economic importance to humans.
Larkin, D M, Yudin, N S
core +1 more source