Results 51 to 60 of about 102,439 (304)

Anion transport inhibitor binding to band 3 in red blood cell membranes. [PDF]

open access: yes, 1983
The inhibitor of anion exchange 4,4'-dibenzoamido-2,2'-disulfonic stilbene (DBDS) binds to band 3, the anion transport protein in human red cell ghost membranes, and undergoes a large increase in fluorescence intensity when bound to band 3.
Dix, JA, Solomon, AK, Verkman, AS
core  

A two-component polymeric optode membrane based on a multifunctional ionic liquid [PDF]

open access: yes, 2011
This work details the use of a 2-component optode membrane which is capable of generating three distinct colours in the presence of Cu2+ and Co2+ ions.
Byrne, Robert   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Chloride binding to the anion transport binding sites of band 3. A 35Cl NMR study [PDF]

open access: yes, 1984
Band 3 is an integral membrane protein that exchanges anions across the red cell membrane. Due to the abundance and the high turnover rate of the band 3 transport unit, the band 3 system is the most heavily used ion-transport system in a typical ...
Chan, Sunney I.   +2 more
core  

pDNA capture using grafted adsorbents [PDF]

open access: yes, 2018
BACKGROUND: ‘Expanded’ composite materials are of interest as an alternative, or as a supplement, to packed-bed chromatography during bioproduct recovery and purification.
Bencina   +24 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

30 μm thin hexamethyl-p-terphenyl poly(benzimidazolium) anion exchange membrane for vanadium redox flow batteries

open access: yesElectrochemistry Communications, 2019
We present the first results of an anion exchange ionomer membrane, hexamethyl-p-terphenyl poly(benzimidazolium) (HMT-PMBI), in a vanadium redox flow battery.
Brian Shanahan   +7 more
doaj   +1 more source

Standard Operating Protocol for Ion-Exchange Capacity of Anion Exchange Membranes

open access: yesFrontiers in Energy Research, 2022
Ion-exchange capacity (IEC) is the measure of a material’s capability to displace ions formerly incorporated within its structure. IEC is a key feature of anion-exchange membranes (AEM), as it determines the AEM’s ability to conduct the ions required to ...
Lan Wang   +7 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Preparation of Two-Layer Anion-Exchange Poly(ethersulfone) Based Membrane: Effect of Surface Modification

open access: yesInternational Journal of Polymer Science, 2016
The present work deals with the surface modification of a commercial microfiltration poly(ethersulfone) membrane by graft polymerization technique. Poly(styrene-co-divinylbenzene-co-4-vinylbenzylchloride) surface layer was covalently attached onto the ...
Lucie Zarybnicka   +3 more
doaj   +1 more source

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