Results 201 to 210 of about 803,233 (296)

Molecular Recognition by Halogen Bonding With Atomic Precision in a Covalent Organic Cage. [PDF]

open access: yesAngew Chem Int Ed Engl
Dupin PA   +9 more
europepmc   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

open access: yesAdvanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng   +8 more
wiley   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

open access: yesAdvanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu   +6 more
wiley   +1 more source

Targeting calcium-crosslinked alginate hydrogel in a living subject using a synthetic anion receptor. [PDF]

open access: yesChem Sci
Cheney HBD   +6 more
europepmc   +1 more source

Elastomeric Core‐Conductive Shell Slurry Additive Stabilizes High‐Voltage NCM811 Cathodes via Mechanical‐Electrical Dual Regulation

open access: yesAdvanced Science, EarlyView.
A core‐shell ASA slurry additive constructs a mosaic‐like interface on high‐voltage NCM811 cathodes. This architecture decouples interfacial functions: the elastomeric core buffers mechanical stress to prevent microcracking, while the conductive shell facilitates rapid ion/electron transport, enabling mechanical‐electrical dual regulation and enhanced ...
Jiamin Duan   +16 more
wiley   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

open access: yesAdvanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li   +7 more
wiley   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

open access: yesAdvanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang   +14 more
wiley   +1 more source

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