Molecular Recognition by Halogen Bonding With Atomic Precision in a Covalent Organic Cage. [PDF]
Dupin PA +9 more
europepmc +1 more source
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng +8 more
wiley +1 more source
Direct energy consumption by inhibitory GABA <sub><i>A</i></sub> receptors: from synaptic mechanisms to network activity. [PDF]
Menzikov SA +4 more
europepmc +1 more source
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu +6 more
wiley +1 more source
Targeting calcium-crosslinked alginate hydrogel in a living subject using a synthetic anion receptor. [PDF]
Cheney HBD +6 more
europepmc +1 more source
A core‐shell ASA slurry additive constructs a mosaic‐like interface on high‐voltage NCM811 cathodes. This architecture decouples interfacial functions: the elastomeric core buffers mechanical stress to prevent microcracking, while the conductive shell facilitates rapid ion/electron transport, enabling mechanical‐electrical dual regulation and enhanced ...
Jiamin Duan +16 more
wiley +1 more source
Molecular Recognition of Steroids and Bile Salts by Substituted Cyclodextrins: The Influence of Gonane Isomerism and Rim Functionalization on Complexation Thermodynamics. [PDF]
Usenik A, Katovčić S, Požar J.
europepmc +1 more source
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li +7 more
wiley +1 more source
Potential Roles of Flavonoids from Chrysanthemi Flos and Chrysanthemi Indici Flos in Modulating Bile Acid Metabolism: Mechanistic Insights and Future Perspectives. [PDF]
Zhao S +5 more
europepmc +1 more source
TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang +14 more
wiley +1 more source

