Results 1 to 10 of about 753,827 (266)

Molecular recognition of thyroglobulin by sortilin [PDF]

Nature Communications
Sortilin is a ubiquitous membrane receptor mediating trafficking of protein cargoes. In the thyroid, sortilin binds thyroglobulin (TG) during its endocytosis, a key process in thyroid homeostasis. Although sortilin has been proposed to recognise highly iodinated TG, the molecular details of this interaction remain unknown.
Irene Boniardi, Giorgia Tanzi, Alessio Di Ianni, Andrea Graziadei, Marko Nedeljković, Camilla Stejskalova, Francesca Coscia   +6 more
openaire   +4 more sources

Aster glehni F. Schmidt Extract Modulates the Activities of HMG-CoA Reductase and Fatty Acid Synthase

Plants, 2021
Aster glehni F. Schmidt (AG), is a natural product known to have anti-obesity effects, but the mechanism underlying these effects is not well documented. We hypothesized that AG may have inhibitory effects on enzymes related to lipid accumulation. Herein,
Hyunbeom Lee, Hyoung Ja Kim, Hyungi Chae, Na Eun Yoon, Byung Hwa Jung   +4 more
doaj   +1 more source

Metabolomics in Autoimmune Diseases: Focus on Rheumatoid Arthritis, Systemic Lupus Erythematous, and Multiple Sclerosis

Metabolites, 2021
The metabolomics approach represents the last downstream phenotype and is widely used in clinical studies and drug discovery. In this paper, we outline recent advances in the metabolomics research of autoimmune diseases (ADs) such as rheumatoid arthritis
Naeun Yoon, Ah-Kyung Jang, Yerim Seo, Byung Hwa Jung   +3 more
doaj   +1 more source

Covalent Organic Framework/Polyacrylonitrile Electrospun Nanofiber for Dispersive Solid-Phase Extraction of Trace Quinolones in Food Samples

Nanomaterials, 2022
The extraction of quinolone antibiotics (QAs) is crucial for the environment and human health. In this work, polyacrylonitrile (PAN)/covalent organic framework TpPa–1 nanofiber was prepared by an electrospinning technique and used as an adsorbent for ...
Jinghui Zhou, An Chen, Hongying Guo, Yijun Li, Xiwen He, Langxing Chen, Yukui Zhang   +6 more
doaj   +1 more source

Surface molecular recognition [PDF]

Proceedings of the National Academy of Sciences, 2001
The spatial display of cellular ligands and receptors is important for cell adhesion and communication. Two approaches that emphasize developing selective methods to dissect, modify, and control receptor–ligand interactions at the cellular interface are discussed.
N S, Sampson, M, Mrksich, C R, Bertozzi
openaire   +2 more sources

A New Ratiometric Fluorescent Probe Based on BODIPY for Highly Selective Detection of Hydrogen Sulfide

Molecules, 2022
Hydrogen sulfide (H2S) as small molecular signal messenger plays key functions in numerous biological processes. The imaging detection of intracellular hydrogen sulfide is of great significance.
Huan Xiang, Tianqing Ye, Yanbo Li, Yanfei Lin, Dan Liu, Hongwei Zhou, Jianbo Wang, Lei Li   +7 more
doaj   +1 more source

A Highly Selective and Sensitive Fluorescent Sensor Based on Molecularly Imprinted Polymer-Functionalized Mn-Doped ZnS Quantum Dots for Detection of Roxarsone in Feeds

Nanomaterials, 2022
Roxarsone (ROX) as an organoarsenic feed additive has been widely used in livestock breeding and poultry industry, but ROX can degrade into highly toxic inorganic arsenic species in natural environments to threaten to the environment and human health ...
Fei Li, Jie Gao, Haocheng Wu, Yijun Li, Xiwen He, Langxing Chen   +5 more
doaj   +1 more source

Stereoselectivity control in Rh-catalyzed β-OH elimination for chiral allene formation

Nature Communications, 2023
Stereoselectivity control and understanding in the metal-catalyzed reactions are fundamental issues in catalysis. Here we report sterically controlled rhodium-catalyzed SN2’-type substitution reactions of optically active tertiary propargylic alcohols ...
Jie Wang, Wei-Feng Zheng, Xue Zhang, Hui Qian, Shengming Ma   +4 more
doaj   +1 more source

DNA Nanodevice-Based Drug Delivery Systems

Biomolecules, 2021
DNA, a natural biological material, has become an ideal choice for biomedical applications, mainly owing to its good biocompatibility, ease of synthesis, modifiability, and especially programmability.
Chaoyang Guan, Xiaoli Zhu, Chang Feng
doaj   +1 more source

Molecular Recognition and Assembly. [PDF]

Acta Chemica Scandinavica, 1996
The synthesis and characterization of a series of self-assembling capsules is described. Assembly takes place as a result of the self-complementary hydrogen bonding patterns on the subunit pieces and dimerization occurs in such a manner that the concave surfaces of the two subunits are directed at one another.
Julius Rebek, Jr., Roman Sakowicz, Valeri Martichonok, James K. Hogan, Marvin Gold, J. Bryan Jones, Kjell Undheim, Connie N. Rosendahl, Monika Haugg, Nathalie Trabesinger-Rüf, Elmar G. Weinhold   +10 more
openaire   +2 more sources