Results 11 to 20 of about 5,633,983 (314)
Image2SMILES: Transformer-based Molecular Optical Recognition Engine [PDF]
, 2021 The rise of deep learning in various scientific and technology areas promotes the development of AI-based tools for information retrieval. Optical recognition of organic structures is a key part of the automated extraction of chemical information ...
Sergey, Sosnin +3 more
core +1 more source
Cells, 2020 Fatty acid synthase (FAS) is a key enzyme involved in de novo lipogenesis that produces lipids that are necessary for cell growth and signal transduction, and it is known to be overexpressed, especially in cancer cells.
Ju Eun Oh +4 more
doaj +1 more source
Scientific Reports, 2022 Selective isolation of soil Actinobacteria was undertaken to isolate a new class of antibiotics and bioactive molecules. A Streptomyces sp. PSAA01 (= MTCC 13,157), isolated from soil of Eastern Himalaya foothill was cultivated on a large scale for the ...
Prasenjit Das +5 more
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Strategies for Enhancing the Sensitivity of Electrochemiluminescence Biosensors
Biosensors, 2022 Electrochemiluminescence (ECL) has received considerable attention as a powerful analytical technique for the sensitive and accurate detection of biological analytes owing to its high sensitivity and selectivity and wide dynamic range.
Yueyue Huang +6 more
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Molecular recognition of the nucleosomal “supergroove” [PDF]
Proceedings of the National Academy of Sciences, 2004 Chromatin is the physiological substrate in all processes involving eukaryotic DNA. By organizing 147 base pairs of DNA into two tight superhelical coils, the nucleosome generates an architecture where DNA regions that are 80 base pairs apart on linear DNA are brought into close proximity, resulting in the formation of DNA ...
Edayathumangalam, Rajeswari S. +4 more
openaire +3 more sources
Xenon binding by a tight yet adaptive chiral soft capsule
Nature Communications, 2020 Xenon binding carries potential for xenon separation and emerging applications in magnetic resonance imaging. Here, the authors report a rare example of a tight yet soft capsule, assembled from two chiral bisurea-bisthiourea macrocycle components, that ...
Shi-Xin Nie +5 more
doaj +1 more source
Supramolecular tessellations by the exo-wall interactions of pagoda[4]arene
Nature Communications, 2021 Supramolecular tessellation has gained increasing interest in supramolecular chemistry for its structural aesthetics and potential applications in optics, magnetics and catalysis.
Xiao-Ni Han, Ying Han, Chuan-Feng Chen
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Palladium-catalysed formation of vicinal all-carbon quaternary centres via propargylation
Nature Communications, 2016 Formation of vicinal, quaternary stereocentres is challenging, but such products are commonly encountered in nature. Here, the authors report a palladium catalysed process to form vicinal quaternary carbons via propargylation, including in enantiopure ...
Xin Huang +5 more
doaj +1 more source
Developments in Molecular Recognition and Sensing at Interfaces
, 2007 In biological systems, molecular recognition events occur mostly withininterfacial environments such as at membrane surfaces, enzyme reaction sites, or at theinterior of the DNA double helix.
Jonathan P. Hill +2 more
core +2 more sources
Catalytic enantioselective construction of axial chirality in 1,3-disubstituted allenes
Nature Communications, 2019 Highly enantioselective synthesis of allenes has been relying, so far, on the steric hindrance of substrates. Here the authors achieve excellent stereocontrol in the synthesis of chiral allenes with a palladium-DTBM-SEGPHOS catalytic system in a non ...
Shihua Song +3 more
doaj +1 more source