Results 101 to 110 of about 209,205 (315)

Sessler, Jonathan L. Pyrrole-based anion receptors : binding studies and progress towards attachment to solid support [PDF]

open access: yes, 2007
textAnions have a wide range of importance both in chemical, as well as biological, systems; thus, the design and synthesis of novel receptors with the ability to selectively recognize or bind a specific class of anions is a rapidly developing field of ...
Barkey, Natalie Marie, 1980-
core  

New Theoretical Model of Nerve Conduction in Unmyelinated Nerves

open access: yesFrontiers in Physiology, 2017
Nerve conduction in unmyelinated fibers has long been described based on the equivalent circuit model and cable theory. However, without the change in ionic concentration gradient across the membrane, there would be no generation or propagation of the ...
Tetsuya Akaishi, Tetsuya Akaishi
doaj   +1 more source

Anion/anion exchange in human neutrophils. [PDF]

open access: yesThe Journal of general physiology, 1986
Of the total one-way chloride fluxes (approximately 1.4 meq/liter cell water X min) in steady state human polymorphonuclear leukocytes bathed in 148 mM Cl media, approximately 70% behaves as self-exchange mediated by a nonselective anion carrier that is not inhibited by stilbene disulfonates.
L, Simchowitz, R, Ratzlaff, P, De Weer
openaire   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Irreversible inhibition of H+-ATPase of higher plant tonoplast by chaotropic anions : evidence for peripheral location of nucleotide-binding subunits. [PDF]

open access: yes, 1987
The H+-translocating ATPase of tonoplast vesicles from storage root of Beta vulgaris L. is irreversibly inhibited by a 30 min treatment with the chaotropic anions SCN−, ClO4−, I− or NO3− in the 0.25–1.5 M concentration range.
Griffith, C. J.   +3 more
core   +1 more source

Carbonic Anhydrase from Porphyromonas Gingivalis as a Drug Target

open access: yesPathogens, 2017
Periodontitis originates from a microbial synergy causing the development of a mouth microbial imbalance (dysbiosis), consisting of a microbial community composed of anaerobic bacteria.
Claudiu T. Supuran, Clemente Capasso
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Effect of irrigation and anions introduced in the form of magnesium salts on selected biochemical quality indices of sandy soil / Wpływ nawadniania oraz anionów wprowadzonych w formie soli magnezowych na wybrane biochemiczne wskaźniki jakości gleby lekkiej

open access: yesEnvironmental Protection and Natural Resources, 2013
In this study, the effect of irrigation and anions introduced in the form of Mg(NO3)2, MgCO3 and MgSO4, which are biochemical indices of soil quality. Two laboratory experiments using complete randomisation were performed.
Chorągwicki Łukasz   +3 more
doaj   +1 more source

Physiology of acid-base balance in bovines with diarrhea backgrounds from Monteria, Colombia

open access: yesRevista Mvz Cordoba, 2015
Objective. Evaluate the acid-base balance (ABB) in bovines with diarrheic backgrounds in four areas of Montería, Colombia. Materials and methods. From a total of 300 pregnant cows, 60 were selected with their newborns.
César Betancur H   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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