Results 91 to 100 of about 22,474 (255)

Considerations on the Haigis formula: Are better outcomes possible with tuning?

Acta Ophthalmologica, Volume 103, Issue 5, Page e298-e309, August 2025.
Abstract Purpose To design a vergence‐based lens power formula based on the classical Haigis formula for better outcomes while retaining the original formula architecture. Methods Four new formula variants (A–D) incorporating a sum of segments correction for axial length, harmonic mean of corneal radii instead of arithmetic mean (all variants), and ...
Achim Langenbucher, Nóra Szentmáry, Jascha Wendelstein, Alan Cayless, Benj Fassbind, Peter Hoffmann   +5 more
wiley   +1 more source

A European perspective on auditory processing disorder-current knowledge and future research focus [PDF]

, 2017
Current notions of \u201chearing impairment,\u201d as reflected in clinical audiological practice, do not acknowledge the needs of individuals who have normal hearing pure tone sensitivity but who experience auditory processing difficulties in everyday ...
Bamiou, Doris-Eva, Barajas, Jose, Brechmann, Andr\ue3\ua9, Callimachou, Marina, Deggouj, Na\ue3\uafma, Demanez, Laurent, Grech, Helen, Hedjever, Mladen, Iliadou, Vasiliki, Kiese-Himmel, Christiane, Konukseven, Ozlem, Kuske, Sandra, Martins, Jorge Humberto, Mattsson, Tone Stokkereit, Nickisch, Andreas, Pedersen, Ellen Raben, Ptok, Martin, Santarelli, Rosamaria, Sirimanna, Tony, Sliwinska-Kowalska, Mariola, Thai-Van, Hung, Veraguth, Dorothy, Veuillet, Evelyne   +22 more
core   +7 more sources

PAX6 gene variations associated with aniridia in south India

BMC Medical Genetics, 2004
Background Mutations in the transcription factor gene PAX6 have been shown to be the cause of the aniridia phenotype. The purpose of this study was to analyze patients with aniridia to uncover PAX6 gene mutations in south Indian population. Methods Total
Shashikant Shetty, Vijayalakshmi Perumalsamy, Krishnadas Subbaiah, Neethirajan Guruswamy, Sundaresan Periasamy   +4 more
doaj   +1 more source

Germline CRISPR/Cas9-Mediated Gene Editing Prevents Vision Loss in a Novel Mouse Model of Aniridia

Molecular Therapy: Methods & Clinical Development, 2020
Aniridia is a rare eye disorder, which is caused by mutations in the paired box 6 (PAX6) gene and results in vision loss due to the lack of a long-term vision-saving therapy.
Seyedeh Zeinab Mirjalili Mohanna, Jack W. Hickmott, Siu Ling Lam, Nina Y. Chiu, Tess C. Lengyell, Beatrice M. Tam, Orson L. Moritz, Elizabeth M. Simpson   +7 more
doaj   +1 more source

Ocular hypertension in myopia: analysis of contrast sensitivity [PDF]

, 2018
Purpose: we evaluated the evolution of contrast sensitivity reduction in patients affected by ocular hypertension and glaucoma, with low to moderate myopia.
Arrico, L, Bianchini, D, Migliorini, R, Nebbioso, M., Quercia, A   +4 more
core   +1 more source

A Distal Model of Congenital Nystagmus as Nonlinear Adaptive Oscillations [PDF]

, 2006
Congenital nystagmus (CN) is an incurable pathological spontaneous oscillation of the eyes with an onset in the first few months of life. The pathophysiology of CN is mysterious.
Berry, David + L, Harris, Christopher + M   +1 more
core   +1 more source

Clinical history and management recommendations of the smooth muscle dysfunction syndrome due to ACTA2 arginine 179 alterations [PDF]

, 2018
Smooth muscle dysfunction syndrome (SMDS) due to heterozygous ACTA2 arginine 179 alterations is characterized by patent ductus arteriosus, vasculopathy (aneurysm and occlusive lesions), pulmonary arterial hypertension, and other complications in smooth ...
A Kikuchi, Alan C Braverman, AN Moosa, Anji Yetman, Anna L Mitchell, Anne Child, Anthony Estrera, AT Yetman, Birgit Lorenz, BL Loeys, Cori Feist, Denver Sallee, Dianna M Milewicz, DJ Schneider, DM Milewicz, Ellen S Regalado, ES Regalado, ES Roach, FM Roulez, Glen Iannucci, Hiroko Morisaki, HU Moller, J de Grazia, J Richer, JL Anderson, John R Ostergaard, Julie De Backer, Julie Richer, Kathryn C Chatfield, Kathryn W Holmes, Lauren Mellor-Crummey, LC Ades, Lesley Ades, LW Fung, M Al-Mohaissen, M Elizabeth Brickner, M Keir, MC Brodsky, ME Meuwissen, MM Georgescu, MR Amans, Mustafa Tekin, NJ Ullrich, P Munot, Patricia Musolino, Paul Mark, Reed Pyeritz, RV Lacro, S Prabhu, Shaine A Morris, Sherene Shalhub, Susan Benedict, T Logeswaran, Takayuki Morisaki, Timothy J Bradley, Y Arlachov   +55 more
core   +3 more sources

Ceratoprótese de Boston tipo I: Revisão [PDF]

, 2012
Regardless of significant progress in the field of corneal transplantation to treat corneal opacification, some cases of corneal blindness still present a poor prognosis for conventional penetrating keratoplasty.
Magalhães, Fernanda Pedreira, Oliveira, Lauro Augusto de, Sousa, Luciene Barbosa de   +2 more
core   +2 more sources

A Synthetic Transcriptional Activator of Genes Associated with the Retina in Human Dermal Fibroblasts. [PDF]

, 2015
Small molecules capable of modulating epigenetic signatures can activate the transcription of tissue-restricted genes in a totally unrelated cell type and have potential use in epigenetic therapy.
Bando, Toshikazu, Chandran, Anandhakumar, Hashiya, Kaori, Kashiwazaki, Gengo, Pandian, Ganesh N, Sato, Shinsuke, Sugiyama, Hiroshi, Syed, Junetha, Taniguchi, Junichi   +8 more
core   +1 more source

Effects of miR-204-5p modulation on PAX6 regulation and corneal inflammation

Scientific Reports
Congenital aniridia is a rare eye disease characterized by loss of PAX6 protein leading to aniridia-associated keratopathy that significantly reduces vision.
Mojdeh Abbasi, Maryam Amini, Petros Moustardas, Quirin Gutsmiedl, Dina Javidjam, Shweta Suiwal, Berthold Seitz, Fabian N. Fries, Ava Dashti, Yedizza Rautavaara, Tanja Stachon, Nóra Szentmáry, Neil Lagali   +12 more
doaj   +1 more source