Results 41 to 50 of about 9,739 (288)

Serotype‐Tailored Midstream and Downstream Operations to Advance the Manufacturing of Adeno‐Associated Viral Vectors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized.
Arianna Minzoni, Shriarjun Shastry, Eduardo Barbieri, Morgan R. Hurst, Kelvin Idanwekhai, Yuxuan Wu, Katherine Ernst, Wai‐Keen Chung, Christopher Bombeck, Saad A. Khan, Sushmita Koley, Gabriella Kiss, Oliver Rammo, Alexander Tropsha, Cristiana Boi, Michael A. Daniele, Steven Cramer, Barry Byrne, Stephen Kaminsky, Angie Snell Bennett, Stefano Menegatti   +20 more
wiley   +1 more source

A Trans‐1,2‐Diphenyl‐Substituted EDTA Platform for High‐Relaxivity Mn(II) MRI Probes

Chemistry – A European Journal, EarlyView.
Symmetric diphenyl substitution of the EDTA backbone enhances the rigidity of the Mn(II) complex and enables strong multisite interactions, providing a versatile platform for further functionalisation and conjugation towards high‐performance Mn(II)‐based MRI contrast agents.
Federico Forgione, Alessandro Nucera, Marco Ricci, Attila Benyei, Mariangela Boccalon, Zsolt Baranyai, Giovanni B. Giovenzana, Mauro Botta   +7 more
wiley   +1 more source

Managing Crystallization in Tin‐Lead Perovskite Solar Cells via Differential Chelating Coordination

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A chelation‐mediated crystallization strategy is developed for Sn–Pb perovskites using 1,10‐phenanthroline. Stronger coordination with Sn than Pb helps reconcile their mismatched crystallization behavior, leading to improved crystalline quality, fewer defects, and reduced oxidation.
Zihao Feng, Miao Zeng, Na Han, Gang Wang, Junmin Xia, Chenpeng Xi, Shi Chen, Jia Guo, Jinfeng Liao, Guichuan Xing   +9 more
wiley   +1 more source

Radical, Not Ionic: The Mechanochemical Zincke Nitration of Phenols

Angewandte Chemie, Volume 138, Issue 46, 9 November 2026.
Mechanochemistry recasts the classical Zincke nitration as an open‐shell process. Liquid‐assisted vibrational milling of phenols with in situ HNO2 delivers direct and ipso nitration across 50 substrates, while atmosphere, NOx‐transfer, EPR and DFT evidence expose a phenoxyl‐radical/NO2 manifold underlying this historically ionic transformation ...
Roberto Scipione, Francesco Basoccu, Pietro Caboni, Francesca Sardu, Enrico Podda, Marco Lucarini, Massimiliano Arca, Andrea Porcheddu   +7 more
wiley   +2 more sources

Pressure dependence of the chlorine NQR in three solid chloro anisoles [PDF]

, 2001
The 35Cl Nuclear Quadrupole Resonance (NQR) frequency (νQ) and spin lattice relaxation time (T1) in the three anisoles 2,3,4-trichloroanisole, 2,3,6-trichloroanisole and 3,5-dichloroanisole have been measured as a function of pressure upto 5.1 kbar at ...
Suresh, K.S., Raghavendra Rao, C., Ramakrishna, J., Ramesh, K.P.   +3 more
core   +1 more source

Comprehensive Review on Advancements in Food Preservation Technologies for Quality and Sustainability

Food Chemistry International, EarlyView.
Preservatives limit microbial development, oxidation, and enzymatic degradation, resulting in better food quality and extended shelf life. Classified as natural, synthetic, or biological, each preservative has distinctive attributes and modes of action. Growing preference for natural preservatives aligns with clean label trends.
Monica Suresh, Arun Meyyazhagan, Haripriya Kuchi Bhotla, Manikantan Pappuswamy, Balamuralikrishnan Balasubramanian   +4 more
wiley   +1 more source

Regulating secondary phase of Rb‐based aggregates for efficient and stable perovskite solar cells

FlexMat, EarlyView.
By introducing RbAc into the precursor solution, the crystallization pathway is optimized, excessive lead iodide is eliminated, grain size increases, and defects are passivated in the perovskite films. The obtained perovskite devices exhibit improved power conversion efficiency and operational stability. Abstract Passivating defects in perovskite films
Weiyuan Chen, Chao Wu, Jie Zhang, Lei Zhao, Yikun Hua, Xinyue Song, Wei Hui, Lin Song   +7 more
wiley   +1 more source

Oxidation of anisoles to p-benzoquinone monoketals catalyzed by a ruthenium complex of 1,4,7-trimethyl-1,4,7-triazacyclononane with tert-butyl hydroperoxide [PDF]

, 2005
A protocol based on [RuIII(Me3tacn)(CF 3CO2)2(H2O)]CF3CO 2 (1, Me3tacn = 1,4,7-trimethyl-1,4,7-triazacyclononane) as catalyst and tert-butyl hydroperoxide (TBHP) as oxidant was developed for oxidation of anisoles to p-benzoquinone monoketals.
Wai‐Hung Cheung, Che, CM, Yu, WY, Chi‐Ming Che, Cheung, WH, Yip, WP, Wing‐Yiu Yu, Wing‐Ping Yip   +7 more
core   +1 more source

Meniscus‐guided organic semiconductor single crystals: From fluid dynamics to morphology control and multifunctional applications

FlexMat, EarlyView.
Centered on the multiscale meniscus, this review dissects mass transport in meniscus‐guided coating into parallel and lateral components. By analyzing the balance of multiple factors during crystallization, it establishes a clear morphology‐performance relationship.
Yumeng Wang, Shengnan Chen, Lutong Guo, Lujing Shao, Zhenhua Li, Hao Liu, Yanlin Song, Yali Qiao   +7 more
wiley   +1 more source

One-pot synthesis of unsymmetrical aryl methylphosphinates by insertion of dichlorophosphines into the O-Me bond of anisoles

, 2001
This letter describes a new one-pot method for the synthesis of unsymmetrical aryl methylphoshinates by insertion of phosphorus moiety into the O-Me bond of anisoles.
Boga C., Baccolini G.
core   +1 more source