Ankylosing Spondylitis (AS) is an autoimmune disease of unknown cause belonging to the group of spondyloarthritides associated with HLA B27. This disease affects the spine and sacroiliac joints, but may also concern peripheral joints and different organs. Symptoms include morning stiffness and dull low back pain, both improving by exercise.
Jeanette, Wolf, Peter, Fasching
openaire +6 more sources
Discovery of fecal microbial signatures in patients with ankylosing spondylitis
Objectives: This study aimed to investigate the characteristics of the gut microbiota in Chinese patients with ankylosing spondylitis (AS) and healthy controls in Quanzhou aiming to explore the correlation between microbiome changes and AS activities.
Yuquan You +6 more
doaj
The seronegative spondyloarthropathies are a group of autoimmune inflammatory diseases lacking rheumatoid factor or antinuclear antibody in their serum. They include ankylosing spondylitis (AS), reactive arthritis, psoriatic arthritis, spondylitis associated with Crohn’s disease and ulcerative colitis, and undifferentiated spondyloarthropathies ...
Nazanin Ebrahimiadib +3 more
openaire +4 more sources
The effect of three years of TNF alpha blocking therapy on markers of bone turnover and their predictive value for treatment discontinuation in patients with ankylosing spondylitis: a prospective longitudinal observational cohort study [PDF]
INTRODUCTION: The aim of this study was to investigate the effect of three years of tumor necrosis factor-alpha (TNF-alpha) blocking therapy on bone turnover as well as to analyze the predictive value of early changes in bone turnover markers (BTM) for ...
Eveline van der Veer +18 more
core +2 more sources
The link between ankylosing spondylitis and inflammatory bowel disease is unclear, however it is hypothesized that there is a causal link between the inheritance of a human leukocyte antigen B27 allele and the development of inflammatory bowel disease ...
Jaclyn Rivington, Michael Gillett
doaj +1 more source
A new and spontaneous animal model for ankylosing spondylitis is found in cynomolgus monkeys
Background Ankylosing spondylitis is a progressive, disabling joint disease that affects millions worldwide. Given its unclear etiology, studies of ankylosing spondylitis relied heavily on drug-induced or transgenic rodent models which retain only ...
Huanhuan Jia +14 more
doaj +1 more source
Increased Risk of Common Orthopedic Surgeries for Patients with Rheumatic Diseases in Taiwan
Background and Objectives: Rheumatic diseases, including rheumatoid arthritis, ankylosing spondylitis, psoriasis, and systemic lupus erythematosus (SLE), are characterized by chronic arthritis or spondyloarthritis, which can lead to joint and spine ...
Min-Chih Hsieh +3 more
doaj +1 more source
ASAS/EULAR recommendations for the management of ankylosing spondylitis [PDF]
Objective: To develop evidence based recommendations for the management of ankylosing spondylitis (AS) as a combined effort of the `ASsessment in AS' international working group and the European League Against Rheumatism.Methods: Each of the 22 ...
Sieper, J. +51 more
core +1 more source
Ankylosing spondylitis: how does it affect the quality of life?
Ankylosing spondylitis is a progressive and debilitating disease known to immensely affect the quality of life and frequently cause disability. There are several instruments that measure this effect, such as Bath Ankylosing Spondylitis Disease Activity ...
Eva Perak +3 more
doaj +1 more source
ASAS/WHO ICF Core Sets for ankylosing spondylitis (AS): how to classify the impact of AS on functioning and health [PDF]
Objective: To report on the results of a standardised consensus process agreeing on concepts typical and/or relevant when classifying functioning and health in patients with ankylosing spondylitis (AS) based on the International Classification of ...
Stucki, Gerold +17 more
core +1 more source

