Results 101 to 110 of about 136,777 (328)

B cells and systemic sclerosis interstitial lung disease

Arthritis &Rheumatology, Accepted Article.
Interstitial lung disease is an important complication of systemic sclerosis (SSc‐ILD) with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to FDA‐approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of interstitial lung diseases of other systemic autoimmune ...
Nina Goldman, Voon Ong, Christopher Denton   +2 more
wiley   +1 more source

TNF blockers inhibit spinal radiographic progression in ankylosing spondylitis by reducing disease activity: results from the Swiss Clinical Quality Management cohort

Annals of the Rheumatic Diseases, 2017
Objectives To analyse the impact of tumour necrosis factor inhibitors (TNFis) on spinal radiographic progression in ankylosing spondylitis (AS). Methods Patients with AS in the Swiss Clinical Quality Management cohort with up to 10 years of follow-up and
Christoph Molnar, A. Scherer, X. Baraliakos, M. de Hooge, R. Micheroli, P. Exer, R. Kissling, G. Tamborrini, L. Wildi, M. Nissen, P. Zufferey, J. Bernhard, U. Weber, R. Landewé, D. M. van der Heijde, A. Ciurea   +15 more
semanticscholar   +1 more source

Impact of diclofenac risk minimization measures addressing cardiovascular risk on analgesic use in musculoskeletal disorders

British Journal of Clinical Pharmacology, EarlyView.
Aims In 2013, risk minimization measures (RMMs) were introduced in Europe to address the increased cardiovascular risk linked to diclofenac. This study aimed to assess the impact of those RMMs on analgesic use. Methods Primary care data from CPRD GOLD (UK) were used.
Tomas Lasys, Yared Santa‐Ana‐Tellez, Satu J. Siiskonen, Daniala L. Weir, Rolf H. H. Groenwold, Helga Gardarsdottir   +5 more
wiley   +1 more source

Clinical efficacy, radiographic and safety findings through 2 years of golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of the randomised, placebo-controlled GO-REVEAL study [PDF]

, 2013
Objectives: To assess long-term golimumab efficacy/safety in patients with active psoriatic arthritis (PsA).<p></p> Methods Adult PsA patients (≥3 swollen, ≥3 tender joints, active psoriasis) were randomly assigned to ...
Beutler, A., Gladman, D.D., Kavanaugh, A., Krueger, G.G., Mack, M., McInnes, I.B., Mease, P.J., Mudivarthy, S., van der Heijde, D., Xu, W., Xu, Z.   +10 more
core   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Reproductive health in women with ankylosing spondylitis: contraception and fertility. A narrative review

Reumatismo
Objective. The knowledge of ankylosing spondylitis is rising, and more and more attention is being paid to the diagnosis of this pathology in females.
L. Marin, A. Andrisani
doaj   +1 more source

Characterization of Patients With Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis in the US‐Based Corrona Registry

Arthritis care & research, 2018
To describe the characteristics of patients with ankylosing spondylitis (AS) and patients with nonradiographic axial spondyloarthritis (SpA) in the US.
P. Mease, D. Heijde, C. Karki, J. Palmer, Mei Liu, R. Pandurengan, Yujin Park, J. Greenberg   +7 more
semanticscholar   +1 more source

Comparison of Surgical Outcomes of the Posterior and Combined Approaches for Repair of Cervical Fractures in Ankylosing Spondylitis. [PDF]

, 2019
STUDY DESIGN: Retrospective cohort study. PURPOSE: To evaluate surgical outcomes and complications of cervical spine fractures in ankylosing spondylitis (CAS) patients who were treated using either the posterior (P) or combined approach (C).
Ariyawatkul, Thanase, Carlson, Victor, Heller, Joshua, Kepler, Christopher K., Luksanapruksa, Panya, Millhouse, Paul William   +5 more
core   +1 more source

Utilization of Proteomic Measures for Early Detection of Drug Benefits and Adverse Effects

The Journal of Clinical Pharmacology, EarlyView.
Abstract Recognition of benefits and adverse effects of therapies in earlier clinical trial phases could improve the safety, efficiency, and cost of clinical trials. Using four clinical trials representing a diverse set of diseases and drug classes (EXSCEL: exenatide/GLP‐1 RA, SUGAR‐DM‐HF: empagliflozin/SGLT2i, PRADA: epirubicin/anthracycline, and ...
Jessica Chadwick, Colin Berry, Meredith A. Carpenter, Geeta Gulati, Siri Lagethon Heck, Michael A. Hinterberg, Rury R. Holman, Matthew M.Y. Lee, Torbjørn Omland, Clare Paterson, Mark C. Petrie, Naveed Sattar, Svati H. Shah, Sama Shrestha, Harald Sourij, Emma V Troth, Victoria Vinje, Stephen A. Williams   +17 more
wiley   +1 more source

The reverse protraction factor in the induction of bone sarcomas in radium-224 patients [PDF]

, 1990
More than 50 bone sarcomas have occurred among a collective of about 800 patients who had been injected in Germany after World War II with large activities of radium-224 for the intended treatment of bone tuberculosis and ankylosing spondylitis.^In an ...
Chmelevsky, D., Kellerer, Albrecht M., Mays, C. W., Spiess, H.   +3 more
core   +1 more source