Results 91 to 100 of about 38,424 (214)
Objective Spondyloarthritides (SpA) and inflammatory bowel disease (IBD) are immune‐mediated diseases with overlap in clinical and immunologic features. However, temporal correlation of SpA and IBD in individual patients and risk factors are not well characterized.
Manasi Agrawal +6 more
wiley +1 more source
ABSTRACT Objective This study aimed to investigate the potential involvement of pyruvate kinase M2 (PKM2) in the pathogenesis of Guillain–Barré syndrome (GBS). Methods Mendelian randomization (MR) analysis was used to evaluate the causal association between PKM2 expression and GBS susceptibility, with mediation analysis performed to explore immune cell‐
Shuping Liu +5 more
wiley +1 more source
Oral Health of Patients With Inflammatory Bowel Disease—A Cross‐Sectional Survey in Austria
ABSTRACT Objective This cross‐sectional survey aimed to assess oral health in patients with inflammatory bowel diseases (IBD) living in Austria. Methods Data collection was conducted with an online questionnaire, including when possible validated tools, covering general medical history, socioeconomic factors, IBD‐related parameters, and various oral ...
Kristina Bertl +6 more
wiley +1 more source
Diagnostic Delay in Ankylosing Spondylitis: Related Factors and Prognostic Outcomes
Objectives: This study aims to evaluate diagnostic delay, factors which are related to diagnostic delay, and the effect of diagnostic delay on prognostic outcomes in terms of spinal and hip mobility, functional status, disease activity, quality of life,
Sasan FALLAHI, Ahmad Reza JAMSHIDI
doaj
ABSTRACT Background While opioid use during pregnancy has raised concerns worldwide, population‐based data in Europe remain limited. In France, little is known about opioid use in the context of pregnancy. Methods We conducted a nationwide drug utilization study using the French EPI‐MERES Registry, derived from the National Health Data System (SNDS ...
Laurent Chouchana +5 more
wiley +1 more source
ABSTRACT Background Rheumatoid arthritis (RA) is a chronic autoimmune disease causing joint inflammation, pain, and deformity, significantly impacting physical and mental well‐being. Sleep disturbances and obesity exacerbate symptoms, increasing disease severity.
Amirabbas Moarefian +4 more
wiley +1 more source
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta +2 more
wiley +1 more source
Background: Ankylosing spondylitis often presents with nonspecific symptoms, making the identification of high-risk individuals challenging in clinical practice. Objective: This study aimed to utilize blood cell indices to construct interpretable machine
Rongqing He +10 more
doaj +1 more source
Metabolic Regulation of Macrophages in Health and Disease
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang +6 more
wiley +1 more source
Objectives: This study aims to evaluate the reliability and validity of the Turkish version of the Short Form of the Social Role Participation Questionnaire (s-SRPQ) in Turkish patients with ankylosing spondylitis.
Yesim AKYOL +4 more
doaj

