Results 91 to 100 of about 59,727 (252)

Effect of transcutaneous electrical nerve stimulation on physical activity and pain evaluation in osteoarthritic dogs

open access: yesVeterinary Record, EarlyView.
Abstract Background Osteoarthritis (OA) causes chronic pain and reduces welfare in dogs. Standard treatments may be inadequate or associated with adverse effects, prompting investigation of alternative therapies. Transcutaneous electrical nerve stimulation (TENS) is a non‐pharmacological pain management method, but evidence for its efficacy in canine ...
Anja Pedersen   +5 more
wiley   +1 more source

Treatment Patterns and Pathways of Systemic Drug Therapy in Patients With Plaque, Erythrodermic, and Generalized Pustular Psoriasis: A Retrospective Cohort Study in Japan

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Systemic psoriasis treatment options have rapidly expanded in Japan, including the approval of tyrosine kinase 2 and interleukin‐36 receptor inhibitors in 2022. However, contemporary real‐world treatment patterns across plaque, erythrodermic, and generalized pustular psoriasis remain incompletely characterized.
Yayoi Tada   +9 more
wiley   +1 more source

Reproductive health in women with ankylosing spondylitis: contraception and fertility. A narrative review

open access: yesReumatismo
Objective. The knowledge of ankylosing spondylitis is rising, and more and more attention is being paid to the diagnosis of this pathology in females.
L. Marin, A. Andrisani
doaj   +1 more source

Exploratory MRI and Clinical Marker Analysis of Pustulotic Arthro‐Osteitis Disease Activity From a Phase 3 Brodalumab Trial

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Pustulotic arthro‐osteitis (PAO) is a clinically important osteoarticular comorbidity affecting approximately 9%–28% of patients with palmoplantar pustulosis (PPP), yet early recognition and standardized activity assessment remain challenging, particularly in routine dermatology practice.
Taiki Nozaki   +8 more
wiley   +1 more source

May Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios Indicate Disease Activity in Ankylosing Spondylitis?

open access: yesThe Turkish Journal of Gastroenterology, 2015
Objectives: This study aims to evaluate the associations between neutrophil-lymphocyte ratio (NLR), mean platelet volume, and platelet lymphocyte ratio (PLR) with disease activity in ankylosing spondylitis.
Esra ERKOL İNAL   +5 more
doaj  

YTHDF3 Enhances Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in Osteoporosis by Promoting TBX19 Expression

open access: yesCell Proliferation, EarlyView.
In this study, OP‐BMSCs were successfully isolated from OVX osteoporotic rats. Mechanistic investigations revealed that the RNA‐binding protein YTHDF3 significantly upregulates Tbx19 expression by enhancing the stability of Tbx19 mRNA. Elevated Tbx19 levels, in turn, activate key osteogenic molecules, effectively promoting the differentiation of OP ...
Qianke Tao   +9 more
wiley   +1 more source

Seronegative spondyloarthropathies : a review : part II: genetics and pathogenesis [PDF]

open access: yes, 1993
In none of the spondyloarthropathies is the pathogenesis well understood. Much of the investigation into the aetio-pathogenesis of these diseases has focused on the association with HLA-B27 and the known triggering potential of certain infectious agents.
Borg, Andrew A.   +2 more
core  

Impact of adalimumab treatment on impairment of non‐professional activities in psoriasis patients

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Psoriasis can result in reduced quality of life, work productivity loss, and a significant restriction in non‐professional activities. This study investigates the effects of long‐term treatment with adalimumab regarding work ability, non‐professional activities, and health‐related quality of life in a large real‐word ...
Georgios Kokolakis   +4 more
wiley   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa Part 1. Epidemiology, diagnosis and clinical assessment

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Updated S2k hidradenitis suppurativa (HS) guidelines provide expert consensus on diagnosis, assessment and comorbidities. Expanded substantially since the 2015 version, they reflect rapid growth in HS literature and aim to improve generalist‐level patient care through evidence‐informed, consensus‐based guidance.
G. B. E. Jemec   +36 more
wiley   +1 more source

Awareness, attitude and practice of home based exercise therapy in diagnosed ankylosing spondylitis patients – A descriptive observational study

open access: yesJournal of Orthopaedic Reports
Background: Ankylosing spondylitis is chronic polyarthritic condition affecting spine and pelvic joints, more prevalent among males than females, appears in early age of 20–40 years. As there are long term symptoms of joint pain, stiffness and functional
Abhijeet Arun Deshmukh   +3 more
doaj   +1 more source

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