Results 101 to 110 of about 38,424 (214)
Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden +3 more
wiley +1 more source
Background Ankylosing spondylitis (AS) is a subtype of arthritis from the axial spondylarthritis spectrum. Involvement of the sacroiliac joints is regarded as an early indicator of ankylosing spondylitis (AS), enabling early detection, and effective ...
Suzan Omar +2 more
doaj +1 more source
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas +11 more
wiley +1 more source
Xujuan Xu,1,* Biyu Shen,2,3,* Aixian Zhang,4 Jingwei Liu,3 Zhanyun Da,4 Hong Liu,4 Zhifeng Gu4 1Department of Nursing, Affiliated Hospital of Nantong University, 2School of Nursing, Nantong University, 3Department of Nursing, The Second Affiliated ...
Xu X +6 more
doaj
Illness Experiences of Young Women With Rheumatoid Arthritis in South Korea
ABSTRACT Background Rheumatoid arthritis affects young women during critical life‐course stages, requiring ongoing adaptation to illness‐related uncertainty while managing social roles and expectations. Women in their 20s to 40s face distinctive challenges related to illness disclosure, stigma and life‐course tasks, particularly around childbirth and ...
Wonhee Baek, Hyunjung Doo
wiley +1 more source
Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha +2 more
wiley +1 more source
In this target trial emulation of patients with immune‐mediated inflammatory diseases and type 2 diabetes, SGLT2 inhibitor initiation was not associated with a clear increase in UTI risk versus metformin, including across immunosuppressive therapy strata.
Hiroshi Tsushima +6 more
wiley +1 more source
Fat infiltration is moderately associated with disease activity in ankylosing spondylitis: a cross-sectional study: Lumbar paraspinal muscles in ankylosing spondylitis. [PDF]
Toprak M, Toprak N.
europepmc +1 more source

