Results 51 to 60 of about 97,289 (321)

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

A case of essential thrombocythemia and ankylosing spondylitis treated with a combination of anagrelide, disease-modifying antirheumatic drugs, and etanercept [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2016
Introduction. A high platelet count, or thrombocytosis, is either a reactive process or a result of a myeloproliferative disorder. Ankylosing spondylitis is a chronic inflammatory rheumatic disease affecting the spine and sometimes peripheral ...
Zeremski Vanja, Savić Aleksandar, Ilić Tatjana, Milošević Ivana, Maksimović Marina, Vučković Biljana   +5 more
doaj   +1 more source

Clinical Significance of Gut Microbiota Community Types for Long‐Term Response to Fecal Microbiota Transplantation in Patients With Psoriatic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Fecal microbiota transplantation (FMT) holds promises as a beneficial supplement to methotrexate in patients with psoriatic arthritis (PsA). We therefore investigated how gut bacterial signatures in patients and donor strain engraftment were associated with long‐term response to FMT.
Panpan Qin, Maja S. Kragsnaes, Dorte K. Holm, Hans Christian Horn, Anna Christine Nilsson, Jens Kjeldsen, Karsten Kristiansen, Torkell Ellingsen   +7 more
wiley   +1 more source

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis [PDF]

, 2017
Background: Dysbiosis has been recently demonstrated in patients with ankylosing spondylitis (AS) but its implications in the modulation of intestinal immune responses have never been studied.
Alessandro, Riccardo, Ciccia, Francesco, Cypers, Heleen, Di Benedetto, Paola, Elewaut, Dirk, Fasano, Alessio, Gabrielli, Armando, Guggino, Giuliana, Luchetti, Michele Maria, Milling, Simon, Rizzo, Aroldo, Saieva, Laura, Stampone, Tommaso, Triolo, Giovanni   +13 more
core   +2 more sources

One‐level mini‐open pedicle subtraction osteotomy for treating spinal kyphosis in patients with ankylosing spondylitis [PDF]

, 2021
Yu Wang, Chunde Li, Long Liu, Longtao Qi
openalex   +1 more source

A Randomized, Placebo‐Controlled Trial of Hydroxychloroquine in Incomplete Lupus

Arthritis &Rheumatology, EarlyView.
Objective Patients with features of systemic lupus erythematosus (SLE) who do not fulfill classification criteria can be designated as incomplete lupus erythematosus (ILE). This condition includes individuals with a high risk of progression to SLE. Treatment of ILE may reduce symptoms, severity, and incidence of SLE.
Nancy J. Olsen, Duanping Liao, Judith A. James, Joel M. Guthridge, Cristina Arriens, Diane Kamen, Mariko Ishimori, Daniel J. Wallace, Christopher Striebich, Sonali Narain, Benjamin F. Chong, Fan He, Eric W. Schaefer, Vernon M. Chinchilli, David R. Karp   +14 more
wiley   +1 more source

Biological and genetic evaluation of IL-23/IL-17 pathway in ankylosing spondylitis patients

Central European Journal of Immunology, 2020
Ankylosing spondylitis is the most common form of the chronic inflammatory disease group known as spondyloarthritides. Recent discoveries of the CD4+ Th17 cells and IL-23/IL-17 axis have changed the paradigms in many autoimmune diseases.
Hulya Deveci, Ayla Turk, Zeliha Ozmen, Ayse Demir, Safiye Coskun   +4 more
doaj   +1 more source

Transition From Psoriasis to Psoriatic Arthritis is Characterized by Distinct Alterations in Peripheral Blood Tc17, Th17, and CD4+ Effector Memory Cells

Arthritis &Rheumatology, EarlyView.
Objective Cellular mechanisms driving transition from psoriasis to psoriatic arthritis have remained largely elusive. Thus, we investigated changes within the peripheral blood T cell compartment associated with the transition phase. Methods In an observational study, 116 patients were examined and categorized into subgroups including psoriasis with at ...
Hanna Graßhoff, Sara Comdühr, Henry Nording, Jacob von Esebeck, Philine Letz, Miriam Prohaczka, Handan Gedik, Henner Zirpel, Elisabeth Spallek, Linh Ha‐Wissel, El‐Baraa Adjailia, Sabrina Arnold, Konstantinos Fourlakis, Sebastian Klapa, Ingo Eitel, Oliver J. Müller, Jens Y. Humrich, Gabriela Riemekasten, Diamant Thaçi, Peter Lamprecht   +19 more
wiley   +1 more source

Ratios of neutrophils to lymphocytes and platelets to lymphocytes in ankylosing spondylitis with disease activity relationship

Advanced Medical Journal
Background and objectives: Ankylosing spondylitis impacts the fibers and synovial tissues of the sacroiliac and spinal joint and is most noticeable commencement occurs in males.
Shahla Taha Ahmad, Shwan Kader Media
doaj   +1 more source

The Impact of Nonsteroidal Anti‐Inflammatory Drugs on Radiographic Spinal Progression in Patients With Axial Spondyloarthritis: 10‐Year Results From an Inception Cohort

Arthritis &Rheumatology, EarlyView.
Objective This study aims to investigate the impact of nonsteroidal anti‐inflammatory drug (NSAID) intake on radiographic spinal progression in axial spondyloarthritis (axSpA), considering different NSAID types (COX‐2 inhibitors [COX2i] and nonselective NSAIDs [ns‐NSAIDs]) and disease subgroups (radiographic [r‐axSpA] and nonradiographic [nr‐axSpA ...
Murat Torgutalp, Valeria Rios Rodriguez, Fabian Proft, Mikhail Protopopov, Judith Rademacher, Hildrun Haibel, Joachim Sieper, Martin Rudwaleit, Denis Poddubnyy   +8 more
wiley   +1 more source