Results 71 to 80 of about 4,734,756 (288)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Performance of conceptual and black-box models in flood warning systems
Cogent Engineering, 2016 Flood forecasting is a core of flood forecasting and flood warning system which can be implemented by both conceptual rainfall–runoff (CRR) model and black-box rainfall–runoff (BBRR) model.
Mohammad Ebrahim Banihabib
doaj +1 more source
The Journal of Engineering, 2019 This study presents a method to predict a day-ahead solar irradiation curve, under extreme meteorological phenomena (Föhn, north and south winds), existing in the province of San Juan, Argentina.
Luis Carlos Parra Raffán +2 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Power Aware Learning for Class AB Analogue VLSI Neural Network
, 2006 Recent research into Artificial Neural Networks (ANN) has highlighted the potential of using compact analogue ANN hardware cores in embedded mobile devices, where power consumption of ANN hardware is a very significant implementation issue.
Brown, Andrew +2 more
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
An application of artificial neural network classifier for medical diagnosis [PDF]
, 2013 In recent year, various models have been proposed for medical diagnosis, which broadly can be classified into physical-based approaches and statistical-based approaches. Uncertainty and imprecision are the most important problems in medical diagnosis,
Khaleel Ibraheem, Amjed
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
CureIt – A Multidisease Predictive System using Machine Learning [PDF]
ITM Web of ConferencesMany contemporary machine learning approaches perform well in predictive analytics on large datasets from many sectors. While predictive analytics in healthcare remains an ambitious goal, it has the potential to enable healthcare practitioners to make ...
Mehta Apoorva S. +2 more
doaj +1 more source