Results 151 to 160 of about 1,073 (201)
BMEMat, EarlyView.A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie +12 more
wiley +1 more source
Trends in Cell Biology, 1993 Annexins have long been though to be involved in exocytosis, possibly by helping to create close interactions between membranes destined to undergo fusion. In this article, we examine recent observations that implicate annexins in three different steps of the endocytic pathway, suggesting that annexins may be universal modulators of membrane ...
Gruenberg, Jean, Emans, Neil
openaire +4 more sources
Annexins as intracellular calcium sensors
Cell Calcium, 2007 The annexins are a multigene family of Ca(2+)- and charged phospholipid-binding proteins. Although they have been ascribed with diverse functions, there is no consensus about the role played by this family as a whole.
Katia Monastyrskaya +2 more
exaly +2 more sources
Annexins—Coordinators of Cholesterol Homeostasis in Endocytic Pathways [PDF]
International Journal of Molecular Sciences, 2018 The spatiotemporal regulation of calcium (Ca2+) storage in late endosomes (LE) and lysosomes (Lys) is increasingly recognized to influence a variety of membrane trafficking events, including endocytosis, exocytosis, and autophagy.
Carles Rentero +2 more
exaly +3 more sources
Comparative Cell Biology and Evolution of Annexins in Diplomonads
MSphere, 2016 Annexins are multifunctional, calcium-binding proteins found in organisms across all kingdoms. Most studies of annexins from single-celled eukaryotes have focused on the alpha-giardins, proteins assigned to the group E annexins, expressed by the ...
Elin Einarsson +2 more
exaly +2 more sources
Parasite annexins – New molecules with potential for drug and vaccine development
BioEssays, 2010 In the last few years, annexins have been discovered in several nematodes and other parasites, and distinct differences between the parasite annexins and those of the hosts make them potentially attractive targets for anti-parasite therapeutics. Annexins
Andreas Hofmann +2 more
exaly +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Biometals, 1998
The annexins are a family of proteins that bind anionic phospholipid surfaces in a Ca(2+)-dependent manner (general reviews include Raynal & Pollard 1994, Swairjo & Seaton 1994, Seaton 1996, Mollenhauer, 1997). Due to this functional property, individual annexins have been discovered independently by numerous laboratories with diverse experimental ...
B A, Seaton, J R, Dedman
openaire +2 more sources
The annexins are a family of proteins that bind anionic phospholipid surfaces in a Ca(2+)-dependent manner (general reviews include Raynal & Pollard 1994, Swairjo & Seaton 1994, Seaton 1996, Mollenhauer, 1997). Due to this functional property, individual annexins have been discovered independently by numerous laboratories with diverse experimental ...
B A, Seaton, J R, Dedman
openaire +2 more sources
Biochemical and Biophysical Research Communications, 2004
The annexins are a family of closely related calcium- and membrane-binding proteins expressed in most eukaryotic cell types. Despite their structural and biochemical similarities annexins have diverse functions, in cellular activities that include vesicle trafficking, cell division, apoptosis, calcium signalling, and growth regulation. To date there is
Matthew J, Hayes, Stephen E, Moss
openaire +2 more sources
The annexins are a family of closely related calcium- and membrane-binding proteins expressed in most eukaryotic cell types. Despite their structural and biochemical similarities annexins have diverse functions, in cellular activities that include vesicle trafficking, cell division, apoptosis, calcium signalling, and growth regulation. To date there is
Matthew J, Hayes, Stephen E, Moss
openaire +2 more sources
Revisiting the role of Annexins in membrane trafficking [PDF]
Cellular and Molecular Life SciencesEver since their discovery five decades ago, annexins have been implicated in membrane-related events along endo- and exocytic pathways. Over the years, structural, biochemical and cell imaging studies have revealed that annexins facilitate the ...
Thomas Grewal +2 more
exaly +2 more sources
A comparison of the energetics of annexin I and annexin V
Journal of Molecular Biology, 1999The annexins comprise a family of soluble Ca2+- and phospholipid-binding proteins. Although highly similar in three-dimensional structure, different annexins are likely to exhibit different biochemical and functional properties and to play different roles in various membrane related events.
A, Rosengarth +3 more
openaire +2 more sources