Results 1 to 10 of about 169,319 (119)

Adaptive immune response in patients with atherosclerosis before and after coronary bypass surgery

open access: yesМедицинский вестник Юга России, 2023
Objective: to assess changes in the immune status before and after coronary bypass surgery. Materials and methods: included 70 male patients with coronary atherosclerosis (group 1) and 30 volunteers (group 2) without signs of coronary artery disease ...
I. F. Shlyk   +5 more
doaj   +1 more source

Pathobiological functions and clinical implications of annexin dysregulation in human cancers

open access: yesFrontiers in Cell and Developmental Biology, 2022
Annexins are an extensive superfamily of structurally related calcium- and phospholipid-binding proteins, largely conserved and widely distributed among species.
Llara Prieto-Fernández   +12 more
doaj   +1 more source

Trafficking of Annexins during Membrane Repair in Human Skeletal Muscle Cells

open access: yesMembranes, 2022
Defects in membrane repair contribute to the development of muscular dystrophies, such as Miyoshi muscular dystrophy 1, limb girdle muscular dystrophy (LGMD), type R2 or R12.
Coralie Croissant   +4 more
doaj   +1 more source

New Insights on Formyl Peptide Receptor Type 2 Involvement in Nociceptive Processes in the Spinal Cord

open access: yesLife, 2022
Formyl peptide receptor type 2 (FPR2/ALX) belongs to the formyl peptide receptors (FPRs) family clustered on chromosome 19 and encodes a family of three Class A of G protein-coupled receptors (GPCRs).
Mariantonella Colucci   +5 more
doaj   +1 more source

Annexin A6 mediates calcium-dependent exosome secretion during plasma membrane repair

open access: yeseLife, 2023
Exosomes are an extracellular vesicle (EV) subtype that is secreted upon the fusion of multivesicular bodies (MVBs) with the plasma membrane. Exosomes may participate in intercellular communication and have utility as disease biomarkers; however, little ...
Justin Krish Williams   +3 more
doaj   +1 more source

Analysis of the Expression and Prognostic Value of Annexin Family Proteins in Bladder Cancer

open access: yesFrontiers in Genetics, 2021
BackgroundBladder cancer (BC) is the most common tumor of the urinary system. Non-muscle-invasive bladder cancer (NMIBC) has a high recurrence rate after surgery, and patients with muscle-invasive bladder cancer (MIBC) have poor quality of life after ...
WenBo Wu   +4 more
doaj   +1 more source

Activated Protein Kinase C (PKC) Is Persistently Trafficked with Epidermal Growth Factor (EGF) Receptor

open access: yesBiomolecules, 2020
Protein kinase Cs (PKCs) are activated by lipids in the plasma membrane and bind to a scaffold assembled on the epidermal growth factor (EGF) receptor (EGFR).
Carol A. Heckman   +3 more
doaj   +1 more source

Membrane Repairing Capability of Non-Small Cell Lung Cancer Cells Is Regulated by Drug Resistance and Epithelial-Mesenchymal-Transition

open access: yesMembranes, 2022
The plasma membrane separates the interior of the cells from the extracellular fluid and protects the cell from disruptive external factors. Therefore, the self-repairing capability of the membrane is crucial for cells to maintain homeostasis and survive
Xingyu Xia   +5 more
doaj   +1 more source

Design and Synthesis of Newly Synthesized Acrylamide Derivatives as Potential Chemotherapeutic Agents against MCF-7 Breast Cancer Cell Line Lodged on PEGylated Bilosomal Nano-Vesicles for Improving Cytotoxic Activity

open access: yesPharmaceuticals, 2021
Cancer is a multifaceted disease. With the development of multi drug resistance, the need for the arousal of novel targets in order to avoid these drawbacks increased. A new series of acrylamide derivatives was synthesized from starting material 4-(furan-
Islam Zaki   +6 more
doaj   +1 more source

The rice annexin gene OsAnn5 is involved in cold stress tolerance at the seedling stage

open access: yesPlant Direct, 2023
Annexins exist widely in plants as multigene families and play critical roles in stress responses and a range of cellular processes. This study provides a comprehensive account of the cloning and functional characterization of the rice annexin gene ...
Zhiqun Que   +3 more
doaj   +1 more source

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