Results 1 to 10 of about 241,609 (354)
Roles of Annexin A protein family in autophagy regulation and therapy
Biomedicine and Pharmacotherapy, 2020 Annexin A is a kind of calcium-dependent phospholipid-binding proteins, which contributes to the formation of the cell membranes and cytoskeleton and played a part as a membrane skeleton to stabilize lipid bilayer.
Yufeng Xi, Rong Ju, Yujia Wang
exaly +2 more sources
Annexin A1 and Autoimmunity: From Basic Science to Clinical Applications
International Journal of Molecular Sciences, 2018 Annexin A1 is a protein with multifunctional roles in innate and adaptive immunity mainly devoted to the regulation of inflammatory cells and the resolution of inflammation. Most of the data regarding Annexin A1 roles in immunity derive from cell studies
Maurizio Bruschi +2 more
exaly +2 more sources
An actin-dependent annexin complex mediates plasma membrane repair in muscle
Journal of Cell Biology, 2016 Demonbreun et al. visualized muscle membrane repair in real time after laser-induced microdamage. Annexin proteins were observed to form a repair cap at the site of injury, supporting a shoulder-like structure containing EHD1, EHD2, dysferlin, and MG53.
Alexis R Demonbreun +2 more
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Adaptive immune response in patients with atherosclerosis before and after coronary bypass surgery
Медицинский вестник Юга России, 2023 Objective: to assess changes in the immune status before and after coronary bypass surgery. Materials and methods: included 70 male patients with coronary atherosclerosis (group 1) and 30 volunteers (group 2) without signs of coronary artery disease ...
I. F. Shlyk +5 more
doaj +1 more source
The Multifaceted Role of Annexin A1 in Viral Infections
Cells, 2023 Dysregulated inflammatory responses are often correlated with disease severity during viral infections. Annexin A1 (AnxA1) is an endogenous pro-resolving protein that timely regulates inflammation by activating signaling pathways that culminate with the ...
Filipe Resende +4 more
semanticscholar +1 more source
Pathobiological functions and clinical implications of annexin dysregulation in human cancers
Frontiers in Cell and Developmental Biology, 2022 Annexins are an extensive superfamily of structurally related calcium- and phospholipid-binding proteins, largely conserved and widely distributed among species.
Llara Prieto-Fernández +12 more
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Annexin‐A1: The culprit or the solution?
Immunology, 2022 Annexin‐A1 has a well‐defined anti‐inflammatory role in the innate immune system, but its function in adaptive immunity remains controversial. This glucocorticoid‐induced protein has been implicated in a range of inflammatory conditions and cancers, as ...
L. Kelly +7 more
semanticscholar +1 more source
Trafficking of Annexins during Membrane Repair in Human Skeletal Muscle Cells
Membranes, 2022 Defects in membrane repair contribute to the development of muscular dystrophies, such as Miyoshi muscular dystrophy 1, limb girdle muscular dystrophy (LGMD), type R2 or R12.
Coralie Croissant +4 more
doaj +1 more source
Annexin A1 as a Regulator of Immune Response in Cancer
Cells, 2021 Annexin A1 is a 37 kDa phospholipid-binding protein that is expressed in many tissues and cell types, including leukocytes, lymphocytes and epithelial cells. Although Annexin A1 has been extensively studied for its anti-inflammatory activity, it has been
T. Araújo +5 more
semanticscholar +1 more source
Life, 2022 Formyl peptide receptor type 2 (FPR2/ALX) belongs to the formyl peptide receptors (FPRs) family clustered on chromosome 19 and encodes a family of three Class A of G protein-coupled receptors (GPCRs).
Mariantonella Colucci +5 more
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