Results 11 to 20 of about 202,359 (295)
Annexin-coated particles induce antigen-specific immunosuppression
Autoimmunity, 2020 Apoptotic cells mediate the development of tolerogenic dendritic cells (DC) and thus facilitate induction and maintenance of peripheral tolerance. Following the identification of the evolutionary conserved annexin core domain (Anx) as a specific signal ...
Corinna Link +3 more
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The role of endogenous annexin A1 on leukocyte biology [PDF]
, 2005 PhDInflammation is the body's innate immune response to the damage caused to its cells and vascularised tissue, either by injury or microbial pathogens.
Yona, Simon
core +4 more sources
New Phytologist, 2010 SummaryAnnexins are multifunctional lipid‐binding proteins. Plant annexins are expressed throughout the life cycle and are under environmental control. Their association or insertion into membranes may be governed by a range of local conditions (Ca2+, pH, voltage or lipid identity) and nonclassical sorting motifs.
Anuphon, Laohavisit, Julia M, Davies
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The translational relevance of the Annexin A1 pathway in inflammatory pathologies: opportunities for novel therapeutic development [PDF]
, 2009 PhDEndogenous anti-inflammatory mediators form a complex network triggered in the host to dampen cell activation and promote resolution of inflammation.
Dalli, Jesmond
core +4 more sources
Investigation into the role of annexin 1 in the microcirculation of annexin 1 knockout mice [PDF]
, 2005 PhDGlucocorticoids are used therapeutically for their anti-inflammatory and immunosuppressive actions. One of the ways they produce their potent effects is via regulation of the anti-inflammatory protein Annexin I (ANX-AI; 37 kDa protein).
Chatterjee, Bristi Emma
core +4 more sources
Annexins and Endocytosis [PDF]
Traffic, 2007 Annexins are calcium‐ and phospholipid‐binding proteins that have been proposed to have multiple roles in membrane traffic. Historically, this has been based on the in vitro properties of annexins and their localization to specific membrane compartments. However, recent functional evidence supports a role for annexins in specific membrane traffic steps,
Clare E, Futter, Ian J, White
openaire +2 more sources
Annexin-Mediated Calcium Signalling in Plants
Plants, 2014 Calcium-permeable channels underpin elevations of free calcium that encode specific signals in stress adaptation, development and immunity. Identifying the genes encoding these channels remains a central goal of plant signalling research.
Julia M. Davies
doaj +1 more source
Annexins and cardiovascular diseases: Beyond membrane trafficking and repair
Frontiers in Cell and Developmental Biology, 2022 Cardiovascular diseases (CVD) remain the leading cause of mortality worldwide. The main cause underlying CVD is associated with the pathological remodeling of the vascular wall, involving several cell types, including endothelial cells, vascular smooth ...
Nerea Méndez-Barbero +10 more
doaj +1 more source
eLife, 2020 Modulating cytoplasmic Ca2+ concentration ([Ca2+]i) by endoplasmic reticulum (ER)-localized inositol 1,4,5-trisphosphate receptor (InsP3R) Ca2+-release channels is a universal signaling pathway that regulates numerous cell-physiological processes ...
Horia Vais +12 more
doaj +1 more source
Annexin A1, A2 and cytokine levels during experimental sepsis in calves [PDF]
The Iranian Journal of Veterinary Science and Technology, 2017 Annexins are fundamentally related proteins that process a variety of physiologic and pathologic procedures, including suppression of inflammation.
Mohammad Reza Mokhber Dezfouli +3 more
doaj +1 more source