Results 11 to 20 of about 241,609 (354)
Annexin-coated particles induce antigen-specific immunosuppression
Autoimmunity, 2020 Apoptotic cells mediate the development of tolerogenic dendritic cells (DC) and thus facilitate induction and maintenance of peripheral tolerance. Following the identification of the evolutionary conserved annexin core domain (Anx) as a specific signal ...
Corinna Link +3 more
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Annexin A1 and annexin A5 in cardiovascular disease [PDF]
, 2021 This study involves two members of the annexin family of proteins and their relationship to cardiovascular disease. The main findings are the inhibiting effect of annexin A5 on clearing away dead cells and, therefore, the enhancing effect on ‘arteriosclerosis’.
Kusters, D.H.M.
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 1997 Annexin V, VI and VII-core (delta1-107) are members of the annexin protein family and bind to acidic phospholipid membranes in a calcium dependent manner. They also show ion channel activity under certain conditions. As annexins bind peripherally to lipid membranes, ion channel formation must consist of at least two steps: An adsorption reaction ...
Hofmann, Andreas +3 more
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New Phytologist, 2010 SummaryAnnexins are multifunctional lipid‐binding proteins. Plant annexins are expressed throughout the life cycle and are under environmental control. Their association or insertion into membranes may be governed by a range of local conditions (Ca2+, pH, voltage or lipid identity) and nonclassical sorting motifs.
Anuphon, Laohavisit, Julia M, Davies
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Annexin A6 mediates calcium-dependent exosome secretion during plasma membrane repair
eLife, 2023 Exosomes are an extracellular vesicle (EV) subtype that is secreted upon the fusion of multivesicular bodies (MVBs) with the plasma membrane. Exosomes may participate in intercellular communication and have utility as disease biomarkers; however, little ...
Justin Krish Williams +3 more
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Analysis of the Expression and Prognostic Value of Annexin Family Proteins in Bladder Cancer
Frontiers in Genetics, 2021 BackgroundBladder cancer (BC) is the most common tumor of the urinary system. Non-muscle-invasive bladder cancer (NMIBC) has a high recurrence rate after surgery, and patients with muscle-invasive bladder cancer (MIBC) have poor quality of life after ...
WenBo Wu +4 more
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Annexin Animal Models—From Fundamental Principles to Translational Research
International Journal of Molecular Sciences, 2021 Routine manipulation of the mouse genome has become a landmark in biomedical research. Traits that are only associated with advanced developmental stages can now be investigated within a living organism, and the in vivo analysis of corresponding ...
T. Grewal +5 more
semanticscholar +1 more source
Annals of Translational Medicine, 2021 Background In recent years, B-cell dysfunction has been found to play an important role in the pathogenesis of primary nephrotic syndrome (PNS). B cells play a pathogenic role by secreting antibodies against their target antigens after transforming into ...
Qing Ye +24 more
semanticscholar +1 more source
Annexins and Endocytosis [PDF]
Traffic, 2007 Annexins are calcium‐ and phospholipid‐binding proteins that have been proposed to have multiple roles in membrane traffic. Historically, this has been based on the in vitro properties of annexins and their localization to specific membrane compartments. However, recent functional evidence supports a role for annexins in specific membrane traffic steps,
Clare E, Futter, Ian J, White
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Biomolecules, 2020 Protein kinase Cs (PKCs) are activated by lipids in the plasma membrane and bind to a scaffold assembled on the epidermal growth factor (EGF) receptor (EGFR).
Carol A. Heckman +3 more
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