Results 1 to 10 of about 747,654 (296)
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2021 In this review, we describe clinical and anatomical prerequisites for the regeneration of injured tympanic membrane, as well as the principles of using composite material LitAr for tympanic membrane repair.
B. M. Zargaryan, S. D. Litvinov
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ER-dependent membrane repair of mycobacteria-induced vacuole damage [PDF]
mBio, 2023 Several intracellular pathogens, such as Mycobacterium tuberculosis, damage endomembranes to access the cytosol and subvert innate immune responses. The host counteracts endomembrane damage by recruiting repair machineries that retain the pathogen inside
Aby Anand +13 more
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Translational implications of targeting annexin A2: From membrane repair to muscular dystrophy, cardiovascular disease and cancer [PDF]
Clinical and Translational Discovery, 2023 Background Annexin A2 contributes to several key cellular functions and processes, including membrane repair. Effective repair prevents cell death and degeneration, especially in skeletal or cardiac muscle, epithelia, and endothelial cells.
Victor G. Kayejo +3 more
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Leveraging Plasma Membrane Repair Therapeutics for Treating Neurodegenerative Diseases [PDF]
Cells, 2023 Plasma membrane repair is an essential cellular mechanism that reseals membrane disruptions after a variety of insults, and compromised repair capacity can contribute to the progression of many diseases.
Hannah R. Bulgart +2 more
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Enhancing Membrane Repair Using Recombinant MG53/TRIM72 (rhMG53) Reduces Neurotoxicity in Alzheimer’s Disease Models [PDF]
BiomoleculesAlzheimer’s Disease (AD) is the most common neurodegenerative disease that involves neuronal cell death initiated by the breakdown of the plasma membrane.
Hannah R. Bulgart +2 more
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Nanodysferlins support membrane repair and binding to TRIM72/MG53 but do not localize to t-tubules or stabilize Ca2+ signaling [PDF]
Molecular Therapy: Methods & Clinical DevelopmentMutations in the DYSF gene, encoding the protein dysferlin, lead to several forms of muscular dystrophy. In healthy skeletal muscle, dysferlin concentrates in the transverse tubules and is involved in repairing the sarcolemma and stabilizing Ca2 ...
Joaquin Muriel +10 more
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Normal Cortical Myelination in Galectin-4-Deficient Mice
Cells, 2022 Myelin, critical for the correct function of the nervous system, is organized in different patterns that can include long non-myelinated axonal segments. How myelin patterning is regulated remains unexplained. The carbohydrate-binding protein galectin-4 (
María Elvira Brocca +8 more
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Impairment of Ceramide-Mediated Endothelial Instant Membrane Resealing During Diabetes Mellitus
Frontiers in Physiology, 2022 Recent studies have indicated that instant cell membrane resealing (ICMR) controls the activation of NOD-like receptor pyrin domain containing 3 (Nlrp3) inflammasomes in endothelial cells, thereby initiating and promoting vascular inflammation.
Yang Chen +6 more
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Open Biology, 2021 The membranes of endosomes, phagosomes and macropinosomes can become damaged by the physical properties of internalized cargo, by active pathogenic invasion or by cellular processes, including endocytic maturation.
Eleanor Childs +3 more
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Current Biology, 2018 Tissue wound repair has been studied extensively. It involves the coordinated activation of several intracellular and intercellular pathways, as well as remodeling from the sequential recruitment of different cell types to the wound site. There is, however, an equally important process that happens at the single cell level, when the integrity of the ...
Norma W, Andrews, Matthias, Corrotte
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