Results 1 to 10 of about 1,082,753 (262)

Membrane Heterogeneity Beyond the Plasma Membrane [PDF]

Frontiers in Cell and Developmental Biology, 2020
The structure and organization of cellular membranes have received intense interest, particularly in investigations of the raft hypothesis. The vast majority of these investigations have focused on the plasma membrane of mammalian cells, yielding ...
Hong-Yin Wang, Deepti Bharti, Deepti Bharti, Ilya Levental   +3 more
doaj   +3 more sources

Yeast Ist2 recruits the endoplasmic reticulum to the plasma membrane and creates a ribosome-free membrane microcompartment. [PDF]

PLoS ONE, 2012
The endoplasmic reticulum (ER) forms contacts with the plasma membrane. These contacts are known to function in non-vesicular lipid transport and signaling.
Wendelin Wolf, Annett Kilic, Bianca Schrul, Holger Lorenz, Blanche Schwappach, Matthias Seedorf   +5 more
doaj   +1 more source

Annexin A2 Mediates Dysferlin Accumulation and Muscle Cell Membrane Repair

Cells, 2020
Muscle cell plasma membrane is frequently damaged by mechanical activity, and its repair requires the membrane protein dysferlin. We previously identified that, similar to dysferlin deficit, lack of annexin A2 (AnxA2) also impairs repair of skeletal ...
Daniel C. Bittel, Goutam Chandra, Laxmi M. S. Tirunagri, Arun B. Deora, Sushma Medikayala, Luana Scheffer, Aurelia Defour, Jyoti K. Jaiswal   +7 more
doaj   +1 more source

Therapeutic Nanobodies Targeting Cell Plasma Membrane Transport Proteins: A High-Risk/High-Gain Endeavor

Biomolecules, 2021
Cell plasma membrane proteins are considered as gatekeepers of the cell and play a major role in regulating various processes. Transport proteins constitute a subclass of cell plasma membrane proteins enabling the exchange of molecules and ions between ...
Raf Van Campenhout, Serge Muyldermans, Mathieu Vinken, Nick Devoogdt, Timo W.M. De Groof   +4 more
doaj   +1 more source

Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation

Cell Reports, 2020
Summary: Plasma membrane damage and cell death during processes such as necroptosis and apoptosis result from cues originating intracellularly. However, death caused by pore-forming agents, like bacterial toxins or complement, is due to direct external ...
Ning Wu, Vitalij Cernysiov, Dominique Davidson, Hua Song, Jianlong Tang, Shanshan Luo, Yan Lu, Jin Qian, Ivayla E. Gyurova, Stephen N. Waggoner, Vincent Quoc-Huy Trinh, Romain Cayrol, Ayumu Sugiura, Heidi M. McBride, Jean-François Daudelin, Nathalie Labrecque, André Veillette   +16 more
doaj   +1 more source

Transport of cholesterol from the endoplasmic reticulum to the plasma membrane is constitutive in CaCo-2 cells and differs from the transport of plasma membrane cholesterol to the endoplasmic reticulum

Journal of Lipid Research, 1998
The transport of newly synthesized cholesterol from its site of synthesis, the endoplasmic reticulum, to the plasma membrane was studied in CaCo-2 cells. The appearance of newly synthesized cholesterol on the cell surface was rapid. By 30 min, 50% of the
F. Jeffrey Field, Ella Born, Shubha Murthy, Satya N. Mathur   +3 more
doaj   +1 more source

High-Resolution Plasma Membrane-Selective Imaging by Second Harmonic Generation

iScience, 2018
Summary: The plasma membrane is the site of intercellular communication and subsequent intracellular signal transduction. The specific visualization of the plasma membrane in living cells, however, is difficult using fluorescence-based techniques owing ...
Takaha Mizuguchi, Masato Yasui, Mutsuo Nuriya   +2 more
doaj   +1 more source

Plasma Membrane Phosphatidylinositol-4-Phosphate Is Not Necessary for Candida albicans Viability yet Is Key for Cell Wall Integrity and Systemic Infection

mBio, 2022
Phosphatidylinositol phosphates are key phospholipids with a range of regulatory roles, including membrane trafficking and cell polarity. Phosphatidylinositol-4-phosphate [PI(4)P] at the Golgi apparatus is required for the budding-to-filamentous-growth ...
Rocio Garcia-Rodas, Hayet Labbaoui, François Orange, Norma Solis, Oscar Zaragoza, Scott G. Filler, Martine Bassilana, Robert A. Arkowitz   +7 more
doaj   +1 more source

Pseudomonas Lipodepsipeptides and Fungal Cell Wall-Degrading Enzymes Act Synergistically in Biological Control

Molecular Plant-Microbe Interactions, 2002
Pseudomonas syringae pv. syringae strain B359 secreted two main lipodepsipeptides (LDPs), syringomycin E (SRE) and syringopeptin 25A (SP25A), together with at least four types of cell wall—degrading enzymes (CWDEs).
Vincenzo Fogliano, Alessandro Ballio, Monica Gallo, Sheridan Woo, Felice Scala, Matteo Lorito   +5 more
doaj   +1 more source

Plasma membrane integrity: implications for health and disease

BMC Biology, 2021
Plasma membrane integrity is essential for cellular homeostasis. In vivo, cells experience plasma membrane damage from a multitude of stressors in the extra- and intra-cellular environment.
Dustin A. Ammendolia, William M. Bement, John H. Brumell   +2 more
doaj   +1 more source