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Membrane Heterogeneity Beyond the Plasma Membrane [PDF]
Frontiers in Cell and Developmental Biology, 2020 The structure and organization of cellular membranes have received intense interest, particularly in investigations of the raft hypothesis. The vast majority of these investigations have focused on the plasma membrane of mammalian cells, yielding ...
Hong-Yin Wang +3 more
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Asymmetry and heterogeneity in the plasma membrane. [PDF]
Biophys JABSTRACT Plasma membranes (PMs) exhibit asymmetry between their two leaflets in terms of phospholipid headgroups, unsaturation, and resulting membrane properties such as packing and fluidity. Lateral heterogeneity, including the formation of lipid domains, is another crucial aspect of PMs with significant biological implications ...
Yamada T, Shinoda W.
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A TRiP to the plasma membrane [PDF]
Temperature, 2015 TRP ion channels are ubiquitously present in the mammalian body and take part in numerous key physiological functions, including temperature sensing, taste perception, osmo-regulation, cardiac function, renal function, development, and glucose homeostasis.
Ghosh, Debapriya, Voets, Thomas
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Yeast Ist2 recruits the endoplasmic reticulum to the plasma membrane and creates a ribosome-free membrane microcompartment. [PDF]
PLoS ONE, 2012 The endoplasmic reticulum (ER) forms contacts with the plasma membrane. These contacts are known to function in non-vesicular lipid transport and signaling.
Wendelin Wolf +5 more
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Current Biology, 2018 Tissue wound repair has been studied extensively. It involves the coordinated activation of several intracellular and intercellular pathways, as well as remodeling from the sequential recruitment of different cell types to the wound site. There is, however, an equally important process that happens at the single cell level, when the integrity of the ...
Norma W, Andrews, Matthias, Corrotte
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The plasma membrane in cardiomyopathy [PDF]
Postgraduate Medical Journal, 1975 Summary A drug-induced change in the fine morphology of the plasma membrane of heart muscle cells is described. Thus, in rabbits the chronic administration of oxyfedrine caused a marked proliferation of the plasma membrane. At the same time the mitochondria became swollen and vacuolated, and there was evidence of lysis of myofibrils ...
W G, Nayler, W, Burian
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Annexin A2 Mediates Dysferlin Accumulation and Muscle Cell Membrane Repair
Cells, 2020 Muscle cell plasma membrane is frequently damaged by mechanical activity, and its repair requires the membrane protein dysferlin. We previously identified that, similar to dysferlin deficit, lack of annexin A2 (AnxA2) also impairs repair of skeletal ...
Daniel C. Bittel +7 more
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Biomolecules, 2021 Cell plasma membrane proteins are considered as gatekeepers of the cell and play a major role in regulating various processes. Transport proteins constitute a subclass of cell plasma membrane proteins enabling the exchange of molecules and ions between ...
Raf Van Campenhout +4 more
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MACROPHAGE PLASMA MEMBRANE [PDF]
The Journal of Experimental Medicine, 1971 Rabbit alveolar macrophages were incubated in vitro with radioactive protein precursors. Plasma membranes were isolated from these cells, dissolved in phenol-urea-acetic acid, and separated by acrylamide gel electrophoresis. 3H-leucine was rapidly incorporated into membrane protein.
Ralph L. Nachman +2 more
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Cell Reports, 2020 Summary: Plasma membrane damage and cell death during processes such as necroptosis and apoptosis result from cues originating intracellularly. However, death caused by pore-forming agents, like bacterial toxins or complement, is due to direct external ...
Ning Wu +16 more
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