Results 21 to 30 of about 747,654 (296)

Tibial Periosteum For The Surgical Perforation [PDF]

open access: yes, 2016
Purpose: Report a successful case of scleral perforation repair, refractive to treatment with bank-scleral graft, using pretibial periosteum graft patch.
Mateo A   +5 more
core   +1 more source

Repair of traumatic lesions to the plasmalemma of neurons and other cells: Commonalities, conflicts, and controversies

open access: yesFrontiers in Physiology, 2023
Neuroscientists and Cell Biologists have known for many decades that eukaryotic cells, including neurons, are surrounded by a plasmalemma/axolemma consisting of a phospholipid bilayer that regulates trans-membrane diffusion of ions (including calcium ...
Marshal L. Mencel, George D. Bittner
doaj   +1 more source

Crystal structures of the human Dysferlin inner DysF domain [PDF]

open access: yes, 2014
Background: Mutations in dysferlin, the first protein linked with the cell membrane repair mechanism, causes a group of muscular dystrophies called dysferlinopathies.
Cole, Ambrose R.   +4 more
core   +1 more source

Deficient Sarcolemma Repair in ALS: A Novel Mechanism with Therapeutic Potential

open access: yesCells, 2022
The plasma membrane (sarcolemma) of skeletal muscle myofibers is susceptible to injury caused by physical and chemical stresses during normal daily movement and/or under disease conditions. These acute plasma membrane disruptions are normally compensated
Ang Li   +6 more
doaj   +1 more source

Calpains, Cleaved Mini-Dysferlin(C72), and L-Type Channels Underpin Calcium-Dependent Muscle Membrane Repair [PDF]

open access: yes, 2013
Dysferlin is proposed as a key mediator of calcium-dependent muscle membrane repair, although its precise role has remained elusive. Dysferlin interacts with a new membrane repair protein, mitsugumin 53 (MG53), an E3 ubiquitin ligase that shows rapid ...
Cooper, ST   +8 more
core   +3 more sources

Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis [PDF]

open access: yes, 2020
Strategies for controlled delivery of therapeutic siRNA into living cells are in high demand as endosomal escape remains the most prominent bottleneck at the intracellular level.
Barriga, Gerardo Garcia-Diaz   +16 more
core   +3 more sources

Dystrophin deficiency exacerbates skeletal muscle pathology in dysferlin-null mice

open access: yesSkeletal Muscle, 2011
Background Mutations in the genes coding for either dystrophin or dysferlin cause distinct forms of muscular dystrophy. Dystrophin links the cytoskeleton to the sarcolemma through direct interaction with β-dystroglycan.
Han Renzhi   +4 more
doaj   +1 more source

MG53 Mitigates Nitrogen Mustard-Induced Skin Injury

open access: yesCells, 2023
Sulfur mustard (SM) and nitrogen mustard (NM) are vesicant agents that cause skin injury and blistering through complicated cellular events, involving DNA damage, free radical formation, and lipid peroxidation.
Haichang Li   +9 more
doaj   +1 more source

Bioengineering of fetal membrane repair

open access: yesSwiss Medical Weekly, 2008
Swiss Medical Weekly, 138 (41-42)
Zisch, A H, Zimmermann, R
openaire   +5 more sources

Evaluating Poloxamers as Agents for Acceleration of Skeletal Muscle Membrane Repair [PDF]

open access: yes, 2018
Sarcolemmal membrane fragility is a major contributor to the pathology of various muscular dystrophies, including Duchenne Muscular Dystrophy (DMD). DMD is a fatal X- linked genetic disorder resulting from a loss of the dystrophin protein.
Rose, Aubrey
core   +1 more source

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