Results 21 to 30 of about 483,797 (293)
Annexin A2 Mediates Dysferlin Accumulation and Muscle Cell Membrane Repair [PDF]
Cells, 2020 Muscle cell plasma membrane is frequently damaged by mechanical activity, and its repair requires the membrane protein dysferlin. We previously identified that, similar to dysferlin deficit, lack of annexin A2 (AnxA2) also impairs repair of skeletal ...
Daniel C. Bittel +7 more
doaj +2 more sources
Current Biology, 2018 Tissue wound repair has been studied extensively. It involves the coordinated activation of several intracellular and intercellular pathways, as well as remodeling from the sequential recruitment of different cell types to the wound site. There is, however, an equally important process that happens at the single cell level, when the integrity of the ...
Norma W, Andrews, Matthias, Corrotte
openaire +2 more sources
Dysferlin and muscle membrane repair [PDF]
Current Opinion in Cell Biology, 2007 The ability to repair membrane damage is conserved across eukaryotic cells and is necessary for the cells to survive a variety of physiological and pathological membrane disruptions. Membrane repair is mediated by rapid Ca(2+)-triggered exocytosis of various intracellular vesicles, such as lysosomes and enlargeosomes, which lead to the formation of a ...
Renzhi, Han, Kevin P, Campbell
openaire +2 more sources
Mechanism for Vipp1 spiral formation, ring biogenesis, and membrane repair. [PDF]
Nat Struct Mol BiolThe ESCRT-III-like protein Vipp1 couples filament polymerization with membrane remodeling. It assembles planar sheets as well as 3D rings and helical polymers, all implicated in mitigating plastid-associated membrane stress.
Naskar S +6 more
europepmc +2 more sources
How to alleviate cardiac injury from electric shocks at the cellular level
Frontiers in Cardiovascular Medicine, 2022 Electric shocks, the only effective therapy for ventricular fibrillation, also electroporate cardiac cells and contribute to the high-mortality post-cardiac arrest syndrome.
Pamela W. Sowa +9 more
doaj +1 more source
The septin cytoskeleton is required for plasma membrane repair [PDF]
EMBO ReportsStephanie Seveau +2 more
exaly +2 more sources
Calcium signaling in membrane repair [PDF]
Seminars in Cell & Developmental Biology, 2015 Resealing allows cells to mend damaged membranes rapidly when plasma membrane (PM) disruptions occur. Models of PM repair mechanisms include the "lipid-patch", "endocytic removal", and "macro-vesicle shedding" models, all of which postulate a dependence on local increases in intracellular Ca(2+) at injury sites.
Xiping, Cheng +3 more
openaire +2 more sources
Plasma membrane integrity in health and disease: significance and therapeutic potential
Cell Discovery, 2021 Maintenance of plasma membrane integrity is essential for normal cell viability and function. Thus, robust membrane repair mechanisms have evolved to counteract the eminent threat of a torn plasma membrane.
Catarina Dias, Jesper Nylandsted
doaj +1 more source
Mouse Models of Genetically Altered Peroxiredoxin 6
Antioxidants, 2019 Peroxiredoxin 6 (Prdx6) has been shown to have three enzymatic activities: peroxidase, phospholipase A2 (PLA2) and acyl transferase. The peroxidase activity is unusual, as it is capable of reducing phospholipid hydroperoxides (as well as hydrogen ...
Sheldon I. Feinstein
doaj +1 more source
Helicobacter pylori Disrupts Host Cell Membranes, Initiating a Repair Response and Cell Proliferation [PDF]
, 2014 Helicobacter pylori (H. pylori), the human stomach pathogen, lives on the inner surface of the stomach and causes chronic gastritis, peptic ulcer, and gastric cancer.
王錦堂;陳炯年 +1 more
core +1 more source