Results 21 to 30 of about 241,609 (354)

The Annexin A2/S100A10 Complex: The Mutualistic Symbiosis of Two Distinct Proteins

open access: yesBiomolecules, 2021
Mutualistic symbiosis refers to the symbiotic relationship between individuals of different species in which both individuals benefit from the association.
Alamelu G. Bharadwaj   +2 more
semanticscholar   +1 more source

Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance

open access: yesCancer Research, 2020
This study elucidates a novel molecular mechanism through which Annexin A6 in CAF-EV activates FAK-YAP by stabilizing β1 integrin at the cell surface of gastric cancer cells and subsequently induces drug resistance.
Tomoyuki Uchihara   +20 more
semanticscholar   +1 more source

Membrane Repairing Capability of Non-Small Cell Lung Cancer Cells Is Regulated by Drug Resistance and Epithelial-Mesenchymal-Transition

open access: yesMembranes, 2022
The plasma membrane separates the interior of the cells from the extracellular fluid and protects the cell from disruptive external factors. Therefore, the self-repairing capability of the membrane is crucial for cells to maintain homeostasis and survive
Xingyu Xia   +5 more
doaj   +1 more source

Design and Synthesis of Newly Synthesized Acrylamide Derivatives as Potential Chemotherapeutic Agents against MCF-7 Breast Cancer Cell Line Lodged on PEGylated Bilosomal Nano-Vesicles for Improving Cytotoxic Activity

open access: yesPharmaceuticals, 2021
Cancer is a multifaceted disease. With the development of multi drug resistance, the need for the arousal of novel targets in order to avoid these drawbacks increased. A new series of acrylamide derivatives was synthesized from starting material 4-(furan-
Islam Zaki   +6 more
doaj   +1 more source

The rice annexin gene OsAnn5 is involved in cold stress tolerance at the seedling stage

open access: yesPlant Direct, 2023
Annexins exist widely in plants as multigene families and play critical roles in stress responses and a range of cellular processes. This study provides a comprehensive account of the cloning and functional characterization of the rice annexin gene ...
Zhiqun Que   +3 more
doaj   +1 more source

Annexin-V stabilizes membrane defects by inducing lipid phase transition

open access: yesNature Communications, 2020
Annexins are abundant cytoplasmic proteins, which bind to membranes that expose negatively charged phospholipids in a Ca2+-dependent manner. During cell injuries, the entry of extracellular Ca2+ activates the annexin membrane-binding ability ...
Yi-Chih Lin, C. Chipot, S. Scheuring
semanticscholar   +1 more source

Annexin A2 in Inflammation and Host Defense

open access: yesCells, 2020
Annexin A2 (AnxA2) is a multifunctional calcium2+ (Ca2+) and phospholipid-binding protein that is expressed in a wide spectrum of cells, including those participating in the inflammatory response.
Valentina Dallacasagrande, K. Hajjar
semanticscholar   +1 more source

Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis [PDF]

open access: yes, 2004
Annexins are Ca(2+)-binding, membrane-fusogenic proteins with diverse but poorly understood functions. Here, we show that during cell cycle progression annexin 11 translocates from the nucleus to the spindle poles in metaphase and to the spindle midzone ...
Alejandra Tomas   +5 more
core   +1 more source

Annexin-Mediated Calcium Signalling in Plants

open access: yesPlants, 2014
Calcium-permeable channels underpin elevations of free calcium that encode specific signals in stress adaptation, development and immunity. Identifying the genes encoding these channels remains a central goal of plant signalling research.
Julia M. Davies
doaj   +1 more source

Annexins and cardiovascular diseases: Beyond membrane trafficking and repair

open access: yesFrontiers in Cell and Developmental Biology, 2022
Cardiovascular diseases (CVD) remain the leading cause of mortality worldwide. The main cause underlying CVD is associated with the pathological remodeling of the vascular wall, involving several cell types, including endothelial cells, vascular smooth ...
Nerea Méndez-Barbero   +10 more
doaj   +1 more source

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