Results 51 to 60 of about 148,429 (293)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Anomalous Diffusion in Chaotic Scattering [PDF]

Physical Review Letters, 1995
The anomalous diffusion is found for peripheral collision of atomic nuclei described in the framework of the molecular dynamics. Similarly as for chaotic billiards, the long free paths are the source of the long-time correlations and the anomalous diffusion.
Srokowski, T., Ploszajczak, M.
openaire   +4 more sources

Local Analysis of Heterogeneous Intracellular Transport: Slow and Fast Moving Endosomes

Entropy, 2021
Trajectories of endosomes inside living eukaryotic cells are highly heterogeneous in space and time and diffuse anomalously due to a combination of viscoelasticity, caging, aggregation and active transport.
Nickolay Korabel, Daniel Han, Alessandro Taloni, Gianni Pagnini, Sergei Fedotov, Viki Allan, Thomas Andrew Waigh   +6 more
doaj   +1 more source

Nonlinear anomalous diffusion equation and fractal dimension: Exact generalized gaussian solution

, 2002
In this work we incorporate, in a unified way, two anomalous behaviors, the power law and stretched exponential ones, by considering the radial dependence of the $N$-dimensional nonlinear diffusion equation $\partial\rho /\partial{t}={\bf \nabla} \cdot ...
A. C. Scott, A. Compte, A. Compte, A. K. Myers-Beaghton, A. R. Plastino, B. O’Shaughnessy, B. O’Shaughnessy, C. Tsallis, D. A. Stariolo, D. A. Stariolo, E. K. Lenzi, G. Drazer, G. E. Uhlenbeck, H. G. E. Hentschel, H. G. E. Hentschel, H. Spohn, I. T. Pedron, J. Buckmaster, J. G. Berryman, J. Klafer, J. M. Carlson, J. Stephenson, K. Takagoshi, L. Borland, L. Borland, L. C. Malacarne, L. C. Malacarne, L. F. Richardson, M. F. Shlesinger, M. F. Shlesinger, R. Metzler, R. Metzler, R. S. Mendes, S. Martinez   +33 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Numerical Method for Solving of the Anomalous Diffusion Equation Based on a Local Estimate of the Monte Carlo Method

Mathematics, 2022
This paper considers a method of stochastic solution to the anomalous diffusion equation with a fractional derivative with respect to both time and coordinates.
Viacheslav V. Saenko, Vladislav N. Kovalnogov, Ruslan V. Fedorov, Dmitry A. Generalov, Ekaterina V. Tsvetova   +4 more
doaj   +1 more source

Anomalous diffusion in quantum Brownian motion with colored noise [PDF]

, 2006
Anomalous diffusion is discussed in the context of quantum Brownian motion with colored noise. It is shown that earlier results follow simply and directly from the fluctuation-dissipation theorem.
A. Einstein, A. Einstein, G. W. Ford, G. W. Ford, J. Klafter, L. I. Schiff, M. P. Langevin, R. Brown, R. Brown, R. F. O’Connell   +9 more
core   +3 more sources

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source