Results 41 to 50 of about 179,944 (311)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Donor Family and Recipient Anonymity: Time for Change [PDF]

, 2019
Purpose Policies and procedures exist in many jurisdictions regarding ‘anonymity’. These prohibit communication between transplant recipients and donor families.
Jan, E., El-Sheikh, T., Shildrick, M., De Luca, E., Poole, J., Abbey, S., Dal, D., Bachmann, I., Carnie, A., Wright, A., Ross, H., McKeever, P.   +11 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

[Name Withheld]: Anonymity and Its Implications [PDF]

, 2006
Anonymity allows the individual to have a voice without having a name. Since the word “anonymous” entered the English language with the advent of the printing press, the implications of being anonymous - and its lexical offspring “anonymity” - have ...
Weicher, Maureen
core  

Relational anonymity in reducing the harms of illicit drug use: accounts of users of dark web- and street-based services in Finland

Harm Reduction Journal
Background Protecting individual anonymity is a common practice in harm reduction (HR), as it can mitigate the fears that may prevent people from accessing services. Protecting anonymity usually means applying for services with a pseudonym.
Johanna Ranta, Teemu Kaskela, Juha Nurmi, Teemu Ruokolainen, Gillian W. Shorter   +4 more
doaj   +1 more source

P4G2Go: A Privacy-Preserving Scheme for Roaming Energy Consumers of the Smart Grid-to-Go

Sensors, 2021
Due to its flexibility in terms of charging and billing, the smart grid is an enabler of many innovative energy consumption scenarios. One such example is when a landlord rents their property for a specific period to tenants.
Aristeidis Farao, Eleni Veroni, Christoforos Ntantogian, Christos Xenakis   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

sharingsomecode/test-anonymity: test-anonymity release 1.0.0 [PDF]

<p>First release for the project test-anonymity</p ...
sharingsomecode
core   +1 more source

Achieving k-anonymity by clustering in attribute hierarchical structures [PDF]

, 2006
. Individual privacy will be at risk if a published data set is not properly deidentified. k-anonymity is a major technique to de-identify a data set. A more general view of k-anonymity is clustering with a constraint of the minimum number of objects in ...
Raymond Chi-wing Wong, Wong, Raymond Chi-Wing, Li, Jiuyong, Jiuyong Li, Pei, Jian, Jian Pei, Fu, Ada Wai-Chee, Ada Wai-chee Fu   +7 more
core   +1 more source