Results 61 to 70 of about 690,729 (282)

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

Advanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li, Yike Chen, Daniel Western, Muhammad Ali, Menghan Liu, Katherine Gong, Ying Xu, Joseph Lowery, David M. Holtzman, Chloe Robins, John D. Eicher, Yen‐Ning Huang, ShiWei Liu, Tamina Park, Andrew J. Saykin, Kwangsik Nho, Mahdi Moqri, Richard C. Mohs, Amelia Farinas, Patricia Moran‐Losada, Hamilton Se‐Hwee Oh, Tony Wyss‐Coray, Carlos Cruchaga   +22 more
wiley   +1 more source

TARANET: Traffic-Analysis Resistant Anonymity at the NETwork layer

, 2018
Modern low-latency anonymity systems, no matter whether constructed as an overlay or implemented at the network layer, offer limited security guarantees against traffic analysis.
Asoni, Daniele E., Barrera, David, Chen, Chen, Danezis, George, Perrig, Adrian, Troncoso, Carmela   +5 more
core   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Content-centric networking using anonymous datagrams [PDF]

2016 IFIP Networking Conference (IFIP Networking) and Workshops, 2016
Using Interests (requests that elicit content) and maintaining per-Interest forwarding state in Pending Interest Tables (PIT) are integral to the design of the Named Data Networking (NDN) and Content-Centric Networking (CCNx) architectures. However, using PITs makes the network vulnerable to Interest-flooding attacks, and PITs can become very large. It
Garcia-Luna-Aceves, J. J., Mirzazad-Barijough, Maziar   +1 more
openaire   +2 more sources

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

Blindspot: Indistinguishable Anonymous Communications [PDF]

, 2014
Communication anonymity is a key requirement for individuals under targeted surveillance. Practical anonymous communications also require indistinguishability - an adversary should be unable to distinguish between anonymised and non-anonymised traffic ...
Gardiner, Joseph, Nagaraja, Shishir
core   +1 more source

Tracing the Attention of Moving Citizens

, 2016
With the widespread use of mobile computing devices in contemporary society, our trajectories in the physical space and virtual world are increasingly closely connected.
Wang, Cheng-Jun, Wu, Lingfei
core   +1 more source

Decoding Naturalistic Episodic Memory with Artificial Intelligence and Brain‐Machine Interface

Advanced Science, EarlyView.
Episodic memory weaves together what, where, and when of experience into a personal narrative. Cutting‐edge AI models may decode this intricate process in real‐life settings, revealing how neural activity encodes naturalistic memories. By merging AI with brain–machine interfaces, researchers are edging closer to mapping and even engineering memory ...
Dong Song
wiley   +1 more source

An Anonymous Routing Protocol with Authenticated Key Establishment in Wireless Ad Hoc Networks

International Journal of Distributed Sensor Networks, 2014
Anonymity is an important concern in wireless communications. Most anonymous routing protocols in ad hoc networks usually assume that a shared secret exists between the sender and the receiver.
Wei Yuan
doaj   +1 more source

Unsupervised Hierarchical Symbolic Regression for Interpretable Property Modeling in Complex Multi‐Variable Systems

Advanced Science, EarlyView.
UHSR translates complex chemical behavior into clear and explainable equations. Applied to thin‐layer chromatography, it automatically uncovers the mathematical rules linking a molecule's structure to its polarity. This approach matches the accuracy of advanced AI while providing interpretable results, earning greater trust from chemists. The method is
Siyu Lou, Chengchun Liu, Dongxiao Zhang, Yuntian Chen, Fanyang Mo   +4 more
wiley   +1 more source