Results 51 to 60 of about 171,342 (242)

Anopheles sundaicus  complex and the presence of Anopheles epiroticus in Indonesia

open access: yesPLOS Neglected Tropical Diseases, 2020
Anopheles sundaicus s.l. est un important vecteur du paludisme principalement présent dans les paysages côtiers de l'ouest et du centre de l'Indonésie. Le complexe d'espèces a une large répartition géographique en Asie du Sud et du Sud-Est et présente une variabilité écologique et comportementale sur son aire de répartition.
Din Syafruddin   +14 more
openaire   +4 more sources

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi   +5 more
wiley   +1 more source

Pengendalian malaria dengan pemanfaatan ikan Oreocromis niloticus sebagai predator larva

open access: yesJurnal Vektor Penyakit, 2022
Oreochromis niloticus is a type of fish that is a natural enemy of Anopheles mosquito larvae, a vector for transmitting malaria. This method can be used as an alternative tools and integrated with other malaria control methods. This study aims to compare
Yahya Yahya   +18 more
doaj   +1 more source

Variations in household microclimate affect outdoor-biting behaviour of malaria vectors [PDF]

open access: yes, 2017
Background: Mosquito behaviours including the degree to which they bite inside houses or outside is a crucial determinant of human exposure to malaria.
Ferguson, Heather M.   +4 more
core   +2 more sources

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza   +2 more
wiley   +1 more source

Sustainable control of Anopheles mosquito population [PDF]

open access: yes, 2014
Despite the widespread use of insecticides, community engagement programmes and preventive measures mosquito borne diseases are growing and new tools to prevent the spread of disease are urgently needed. An alternative control measure for the eradication
Birch, Philip   +5 more
core   +1 more source

Anopheles (Anopheles) messeae Falleroni 1926

open access: yes, 2022
23. Anopheles (Anopheles) messeae Falleroni, 1926 (Fig. 4E) Published source: Kirik et al. (2020: 5). Voucher material: 1♀, Punaküla (58° 20′ 9″ N, 25° 20′ 4″ E), 31.V.–03.VI.2018, H. Kirik leg., H. Kirik det., Mosquito Magnet trap, IZBE0210221, GenBank: OK465170; 1♀, Tartu (58° 21′ 26″ N, 26° 42′ 60″ E), 04.IX.2017, T. Kesküla leg., H.
Kirik, Heli   +2 more
openaire   +2 more sources

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood   +7 more
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

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