Results 61 to 70 of about 140,817 (245)

Horizontal Transmission of the Symbiont Microsporidia MB in Anopheles arabiensis

Frontiers in Microbiology, 2021
The recently discovered Anopheles symbiont, Microsporidia MB, has a strong malaria transmission-blocking phenotype in Anopheles arabiensis, the predominant Anopheles gambiae species complex member in many active transmission areas in eastern Africa.
G. Nattoh, Tracy Maina, E. E. Makhulu, Lilian Mbaisi, Enock M. Mararo, F. G. Otieno, Tullu Bukhari, T. Onchuru, Evan Teal, Juan C. Paredes, J. Bargul, D. Mburu, E. A. Onyango, G. Magoma, S. Sinkins, J. Herren   +15 more
semanticscholar   +1 more source

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

Clinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi, Mwila Mulubwa, Mmakwena M. Mmonwa, Mathew Njoroge, Liezl Krugmann, Kelly Chibale   +5 more
wiley   +1 more source

Panoramic view of diversity and function of cuticular proteins in insects and mosquitoes biology

Frontiers in Insect Science
AimThe insect cuticle, vital for structural maintenance, forms their exoskeleton. It is mainly composed of an intermesh of – structural cuticle proteins (CPs) with polysaccharide chitin. The insect CPs encoded by CP genes are indispensable for morphology,
Yamini Thakur, Yamini Thakur, Sanjay Tevatiya, Gaurav Kumar, Meenakshi Jeena, Meenakshi Jeena, Vaishali Verma, Vaishali Verma, Rajnikant Dixit, Rajnikant Dixit, Shweta Pasi, Alex Eapen, Alex Eapen, Jaspreet Kaur, Jaspreet Kaur   +14 more
doaj   +1 more source

The Malaria Season Is Upon Us

South African Family Practice, 2016
The arrival of our summer rains brings with it Anopheles mosquitos buzzing around our ankles with the prospect of a nutritious meal. Unbeknownst to the female Anopheles mosquito, she has increased the risk of our becoming an annual statistic by being ...
R. L. van Zyl
doaj   +1 more source

Anopheles (Anopheles) algeriensis Theobald 1903

, 2022
Published as part of Kirik, Heli, Tummeleht, Lea & Kurina, Olavi, 2022, Rediscovering the mosquito fauna (Diptera: Culicidae) of Estonia: an annotated checklist with distribution maps and DNA evidence, pp.
Kirik, Heli, Tummeleht, Lea, Kurina, Olavi   +2 more
openaire   +2 more sources

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Colonization of Anopheles occidentalis and Anopheles hermsi.

Journal of the American Mosquito Control Association, 1990
The colonization of Anopheles occidentalis is described and contrasted with colonization of a related species, An. hermsi. The latter species formerly was considered to be conspecific with the former, but the 2 species differ considerably in biological characteristics.
K K, Fujioka, A R, Barr, P, Guptavanij, D M, Menchaca   +3 more
openaire   +4 more sources

Pengendalian malaria dengan pemanfaatan ikan Oreocromis niloticus sebagai predator larva

Jurnal Vektor Penyakit, 2022
Oreochromis niloticus is a type of fish that is a natural enemy of Anopheles mosquito larvae, a vector for transmitting malaria. This method can be used as an alternative tools and integrated with other malaria control methods. This study aims to compare
Yahya Yahya, Santoso Santoso, Lasbudi Pertama Ambarita, Milana Salim, Indah Margarethy, Rahman Irpan Pahlepi, Yanelza Supranelfy, Rizki Nurmaliani, Nungki Hapsari Suryaningtyas, Vivin Mahdalena, Maya Arisanti, Desi Asyati, Rahayu Hasti Komaria, Surakhmi Oktavia, Katarina Sri Rahayu, Hendri Erwadi, Nur Inzana, Betriyon Betriyon, Dheli Ofarimawan Pratomo   +18 more
doaj   +1 more source

Anopheles (Anopheles) messeae Falleroni 1926

, 2022
23. Anopheles (Anopheles) messeae Falleroni, 1926 (Fig. 4E) Published source: Kirik et al. (2020: 5). Voucher material: 1♀, Punaküla (58° 20′ 9″ N, 25° 20′ 4″ E), 31.V.–03.VI.2018, H. Kirik leg., H. Kirik det., Mosquito Magnet trap, IZBE0210221, GenBank: OK465170; 1♀, Tartu (58° 21′ 26″ N, 26° 42′ 60″ E), 04.IX.2017, T. Kesküla leg., H.
Kirik, Heli, Tummeleht, Lea, Kurina, Olavi   +2 more
openaire   +2 more sources

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source