Results 21 to 30 of about 2,368 (162)

Dual effector population modification gene-drive strains of the African malaria mosquitoes, Anopheles gambiae and Anopheles coluzzii. [PDF]

Proc Natl Acad Sci U S A, 2023
Proposed genetic approaches for reducing human malaria include population modification, which introduces genes into vector mosquitoes to reduce or prevent parasite transmission. We demonstrate the potential of Cas9/guide RNA (gRNA)–based gene-drive systems linked to dual antiparasite effector genes to spread rapidly through mosquito ...
Carballar-Lejarazú R, Dong Y, Pham TB, Tushar T, Corder RM, Mondal A, Sánchez C HM, Lee HF, Marshall JM, Dimopoulos G, James AA.   +10 more
europepmc   +5 more sources

A PCR-RFLP method for genotyping of inversion 2Rc in Anopheles coluzzii [PDF]

Parasites & Vectors, 2021
Abstract Background Genotyping of polymorphic chromosomal inversions in malaria vectors such as An. coluzzii Coetzee & Wilkerson is important, both because they cause cryptic population structure that can mislead vector analysis and control and because they influence epidemiologically relevant eco-phenotypes.
Montanez Gonzalez, Raquel, Vallera, Alexandra, Calzetta, Maria, Pichler, Verena, Love, Rachel, Guelbeogo, Moussa, Dabiré, Roch Kounbobr, Pombi, Marco, Costantini, Carlo, Simard, Frédéric, Della Torre, Alessandra, Besansky, Nora   +11 more
openaire   +4 more sources

The resting behavior of malaria vectors in different ecological zones of Ghana and its implications for vector control

Parasites & Vectors, 2022
Background In sub-Saharan Africa there is widespread use of long-lasting insecticidal nets and indoor residual spraying to help control the densities of malaria vectors and decrease the incidence of malaria.
Akua Obeng Forson, Isaac A. Hinne, Shittu B. Dhikrullahi, Isaac Kwame Sraku, Abdul Rahim Mohammed, Simon K. Attah, Yaw Asare Afrane   +6 more
doaj   +1 more source

Assessment of the ecologically dependent post-zygotic isolation between Anopheles coluzzii and Anopheles gambiae

PLOS ONE, 2020
Within the Anopheles gambiae complex, the sibling species An. coluzzii and An. gambiae are undergoing sympatric speciation. These species are characterized by rare hybrids in most of their geographical distribution. A strong assortative mating mediated by spatial swarm segregation has been shown whereas no intrinsic post-zygotic barriers have been ...
Abdoulaye Niang, Simon Péguédwindé Sawadogo, Roch K. Dabiré, Frederic Tripet, Abdoulaye Diabaté   +4 more
openaire   +4 more sources

Chemosensory gene expression in olfactory organs of the anthropophilic Anopheles coluzzii and zoophilic Anopheles quadriannulatus [PDF]

BMC Genomics, 2017
Anopheles (An.) coluzzii, one of Africa's primary malaria vectors, is highly anthropophilic. This human host preference contributes greatly to its ability to transmit malaria. In contrast, the closely related An. quadriannulatus prefers to feed on bovids and is not thought to contribute to malaria transmission.
Athrey, Giridhar, Cosme, Luciano V., Popkin-Hall, Z., Pathikonda, Sharmila, Takken, W., Slotman, Michel A.   +5 more
openaire   +4 more sources

The Anopheles coluzzii microbiome and its interaction with the intracellular parasite Wolbachia [PDF]

Scientific Reports, 2020
AbstractWolbachia, an endosymbiotic alpha-proteobacterium commonly found in insects, can inhibit the transmission of human pathogens by mosquitoes. Biocontrol programs are underway usingAedes aegyptimosquitoes trans-infected with a non-naturalWolbachiastrain to reduce dengue virus transmission.
Straub, Timothy J., Shaw, W. Robert, Marcenac, Perrine, Sawadogo, Simon P., Dabiré, Roch K., Diabaté, Abdoulaye, Catteruccia, Flaminia, Neafsey, Daniel E.   +7 more
openaire   +2 more sources

Peptides with Antimicrobial Activity in the Saliva of the Malaria Vector Anopheles coluzzii. [PDF]

Int J Mol Sci
Mosquito saliva plays a crucial physiological role in both sugar and blood feeding by helping sugar digestion and exerting antihemostatic functions. During meal acquisition, mosquitoes are exposed to the internalization of external microbes. Since mosquitoes reingest significant amounts of saliva during feeding, we hypothesized that salivary ...
Bevivino G, Maurizi L, Ammendolia MG, Longhi C, Arcà B, Lombardo F.   +5 more
europepmc   +3 more sources

The role of grass volatiles on oviposition site selection by Anopheles arabiensis and Anopheles coluzzii [PDF]

Malaria Journal, 2017
The reproductive success and population dynamics, of Anopheles malaria mosquitoes is strongly influenced by the oviposition site selection of gravid females. Mosquitoes select oviposition sites at different spatial scales, starting with selecting a habitat in which to search.
Asmare, Yelfwagash, Hill, Sharon R., Hopkins, Richard J., Tekie, Habte, Ignell, Rickard   +4 more
openaire   +2 more sources

Population Genetics ofAnopheles coluzziiImmune Pathways and Genes

G3 Genes|Genomes|Genetics, 2015
AbstractNatural selection is expected to drive adaptive evolution in genes involved in host–pathogen interactions. In this study, we use molecular population genetic analyses to understand how natural selection operates on the immune system of Anopheles coluzzii (formerly A. gambiae “M form”).
Rottschaefer, S. M.Crawford, J. E.Riehle, M. M.Guelbeogo, W. M.Gneme, A.Sagnon, N.Vernick, K. D.Lazzaro, B. P.   +8 more
openaire   +2 more sources

Patterns of Gene Flow in Anopheles coluzzii Populations From Two African Oceanic Islands. [PDF]

Evol Appl
ABSTRACTThe malaria vector Anopheles coluzzii is widespread across West Africa and is the sole vector species on the islands of São Tomé and Príncipe. Our interest in the population genetics of this species on these islands is part of an assessment of their suitability for a field trial involving the release of genetically engineered A. coluzzii.
Campos M, Rašić G, Viegas J, Cornel AJ, Pinto J, Lanzaro GC.   +5 more
europepmc   +6 more sources